水产学报2026，Vol.50Issue(5)：18-32,15.DOI:10.11964/jfc.20260315466
环境雌激素对鱼类生长与繁殖的影响
Implications of environmental estrogens for fish growth and reproduction
摘要
Abstract
Environmental estrogens,as typical endocrine-disrupting chemicals widely present in aquatic environments,can exert sustained effects on the growth,development,reproductive processes,immune function,and population structure of fish by disrupting endocrine homeostasis.This review systematically summarizes the research progress on the effects of environ-mental estrogens on fish growth and reproduction,focusing on aspects such as reproductive physiology and sex differentiation,expression and regulation of development-related genes,changes in immune function,and population-level responses.Avail-able studies have shown that environmental estrogens can interfere with gonadal development and sex differentiation by regu-lating the expression of estrogen receptors,vitellogenin,and genes involved in sex hormone synthesis.They can also alter immune cell activity,thymus development,and the expression of immune-related factors,thereby impairing immune defense capabilities in fish.At the population level,environmental estrogens may lead to skewed sex ratios,reduced fecundity,abnor-mal behaviors,and population decline.However,research on long-term low-concentration exposure,combined exposure to multiple pollutants,and transgenerational effects remains relatively insufficient,and the underlying mechanisms and associated ecological risks warrant further investigation.Looking ahead,the regulatory networks underlying the multi-level responses of fish to environmental estrogens—from the molecular and individual levels to the population level would be elucidated,by integrating multi-omics analyses,long-term exposure experiments using ecologically relevant con-centrations,and multigenerational tracking.Thus,this work would provide a theoretical foundation and practical guidance for ecological risk assessment of environmental estrogens,pollution control in aquatic environments,and the conservation of fish resources and sustainable aquaculture.关键词
鱼类/环境雌激素/生长与繁殖/内分泌干扰/生态风险Key words
fish/environmental estrogens/growth and reproduction/endocrine disruption/ecological risks分类
生物科学引用本文复制引用
周志锋,陈鑫,李胜男,周蓉,陶敏..环境雌激素对鱼类生长与繁殖的影响[J].水产学报,2026,50(5):18-32,15.基金项目
国家自然科学基金(U24A20455,32293253) （U24A20455,32293253）
岳麓山实验室种业专项(YLS-2025-ZY01011) （YLS-2025-ZY01011）
国家现代农业产业技术体系(CARS-45) National Natural Science Foundation of China(U24A20455,32293253) （CARS-45）
the Yuelushan Laboratory Breed-ing Program(YLS-2025-ZY01011) （YLS-2025-ZY01011）
China Agriculture Research System(CARS-45) （CARS-45）
