药学研究2026，Vol.45Issue(3)：304-311,345,9.DOI:10.13506/j.cnki.jpr.2026.03.009
海洋生物来源抗肿瘤寡肽的研究进展
Research progress on anti-tumor oligopeptides derived from marine organisms
摘要
Abstract
Cancer remains one of the leading causes of mortality worldwide,making the development of antineoplastic drugs a critical focus in medical research.In recent years,the unique and complex characteristics of marine organisms have attracted increasing attention,prompting extensive exploration of their bioactive compounds.Numerous studies have demonstrated that oligopeptides derived from marine organisms can exert anti-tumor effects through the induction of apoptosis.Small molecular peptides offer advantages such as rapid absorption and efficient cellular and tissue penetration,making them promising candidates for targeted anti-cancer therapies.However,the identification and underlying mechanisms of action of marine-derived oligopeptides are still under investigation.This article provides a comprehensive review of anti-tumor oligopeptides isolated from various marine species,categorized by their biological sources.关键词
海洋生物/抗肿瘤作用/寡肽Key words
Marine organisms/Antitumor effects/Oligopeptides分类
医药卫生引用本文复制引用
苏均宇,丁鸿燕,庄满娇,刘义,邹丽宜..海洋生物来源抗肿瘤寡肽的研究进展[J].药学研究,2026,45(3):304-311,345,9.基金项目
国家自然科学基金项目(No.82204435) （No.82204435）
