上海针灸杂志2026，Vol.45Issue(4)：389-395,7.DOI:10.13460/j.issn.1005-0957.2026.04.0389
靳三针联合中药治疗肝胃不和型功能性消化不良的疗效观察
Efficacy of Jin's three-needle therapy combined with Chinese herbal medicine in the treatment of functional dyspepsia with liver-stomach disharmony pattern
摘要
Abstract
Objective To observe the clinical efficacy of Jin's three-needle therapy combined with Chai Hu Shu Gan powder and Zuo Jin pill in the treatment of functional dyspepsia with liver-stomach disharmony pattern,and its effects on gastrointestinal hormones and brain-gut peptides.Method A total of 80 patients with functional dyspepsia with liver-stomach disharmony pattern were selected and divided into a control group and an observation group according to a random number table method,with 40 cases in each group.The control group was treated with oral Chai Hu Shu Gan powder combined with Zuo Jin pill,while the observation group received Jin's three-needle therapy in addition to the oral herbal treatment used in the control group.The clinical efficacy was compared between the two groups.Changes in traditional Chinese medicine(TCM)pattern scores,clinical symptom scores,functional dyspepsia quality of life(FDQOL)scores,4 h gastric emptying rate,serum gastrointestinal hormones[motilin(MTL),gastrin(GAS),cholecystokinin(CCK),and vasoactive intestinal peptide(VIP)],and brain-gut peptides[5-hydroxytryptamine(5-HT)and substance P(SP)]were observed before and after treatment.Result The total effective rate in the observation group was higher than that in the control group(P＜0.05).After treatment,TCM pattern scores,clinical symptom scores,and serum levels of CCK,VIP,5-HT,and SP in both groups decreased compared with those before treatment(P＜0.05),and those in the observation group were lower than those in the control group(P＜0.05).After treatment,the 4 h gastric emptying rate,serum levels of MTL and GAS,and FDQOL scores in both groups increased compared with those before treatment(P＜0.05),and those in the observation group were higher than those in the control group(P＜0.05).Conclusion Jin's three-needle therapy combined with Chai Hu Shu Gan powder and Zuo Jin pill can significantly improve clinical symptoms and quality of life in patients with functional dyspepsia with liver-stomach disharmony pattern.Its clinical efficacy is superior to that of herbal medicine alone,and the mechanism may be related to regulating gastrointestinal hormones and brain-gut peptides and promoting gastric emptying.关键词
针刺疗法/靳三针/针药并用/功能性消化不良/肝胃不和Key words
Acupuncture therapy/Jin's three-needle therapy/Acupuncture medication combined/Functional dyspepsia/Liver-stomach disharmony分类
医药卫生引用本文复制引用
王雪丹,林占美,杨金旭,司秋霞,张倩..靳三针联合中药治疗肝胃不和型功能性消化不良的疗效观察[J].上海针灸杂志,2026,45(4):389-395,7.基金项目
河北省中医药管理局科研项目(2025171) （2025171）
