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Natural compound DOCA blocks TNF-α/TNFR-driven NF-κB activation to ameliorate rheumatoid arthritis

Chunxia Gan Huanhuan Xu Titi Liu Fei Chen Jin Li Jing Xu Zhe Jiang Hongkang Zhu Chaoyi Xue Jun Sheng

食品科学与人类健康（英文）2026，Vol.15Issue(3)：1426-1442,17.

食品科学与人类健康（英文）2026，Vol.15Issue(3)：1426-1442,17.DOI:10.26599/FSHW.2025.9250909

Natural compound DOCA blocks TNF-α/TNFR-driven NF-κB activation to ameliorate rheumatoid arthritis

Chunxia Gan ¹Huanhuan Xu ²Titi Liu ²Fei Chen ³Jin Li ⁴Jing Xu ⁴Zhe Jiang ⁴Hongkang Zhu ⁵Chaoyi Xue ⁴Jun Sheng⁴

作者信息

1. Key Laboratory of Development and Utilization of Food and Medicinal Resources,Ministry of Education,Yunnan Agricultural University,Kunming 650201,China||Faculty of Modern Tourism and Catering Industry,Kunming University,Kunming 650214,China
2. Key Laboratory of Development and Utilization of Food and Medicinal Resources,Ministry of Education,Yunnan Agricultural University,Kunming 650201,China||College of Science,Yunnan Agricultural University,Kunming 650201,China
3. Key Laboratory of Development and Utilization of Food and Medicinal Resources,Ministry of Education,Yunnan Agricultural University,Kunming 650201,China||School of Life and Environmental Sciences,Huang Shan University,Huangshan 245041,China
4. Key Laboratory of Development and Utilization of Food and Medicinal Resources,Ministry of Education,Yunnan Agricultural University,Kunming 650201,China
5. Food Science and Engineering,Yangzhou University,Yangzhou 215000,China
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摘要

关键词

Tumor necrosis factor-α(TNF-α)/TNF-α receptor(TNFR)/TNF-α-TNFR interaction/Nuclear factor-kappa B signaling/Rheumatoid arthritis

Key words

Tumor necrosis factor-α(TNF-α)/TNF-α receptor(TNFR)/TNF-α-TNFR interaction/Nuclear factor-kappa B signaling/Rheumatoid arthritis

引用本文复制引用

Chunxia Gan,Huanhuan Xu,Titi Liu,Fei Chen,Jin Li,Jing Xu,Zhe Jiang,Hongkang Zhu,Chaoyi Xue,Jun Sheng..Natural compound DOCA blocks TNF-α/TNFR-driven NF-κB activation to ameliorate rheumatoid arthritis[J].食品科学与人类健康（英文）,2026,15(3):1426-1442,17.

基金项目

This work was supported by the National Natural Science Foundation of China(82404638),the Xingdian Talent Plan of Yunnan Province(XDYC-QNRC-2023-0427),the Hainan Provincial Key Research and Development Program(ZDYF2025SXLH005),the Yuanjiang County Dry-Hot Valley Industrial Development Cooperation Special Program,and the Research and Development Special Fund of Zhejiang Damingtang Biotechnology Co.,Ltd. （82404638）

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