实用中医内科杂志2026，Vol.40Issue(4)：45-49,5.DOI:10.13729/j.issn.1671-7813.Z25060905
香砂六君子汤治疗功能性消化不良的研究进展
Research Progress of Xiangsha Liujunzi Decoction in the Treatment of Functional Dyspepsia
摘要
Abstract
Functional dyspepsia(FD)is a gastrointestinal disorder characterized by complex pathological mechanisms,pro-longed disease course,and significant impairment of patients'quality of life.In traditional Chinese medicine(TCM),FD falls under the categories of ＂stomach stuffiness＂and ＂stomach pain＂with its pathogenesis attributed to spleen deficiency with qi stagnation and impaired stomach descending function.Xiangsha Liujunzi decoction,a classic TCMformula,exhibits therapeutic effects including strengthening the spleen,replenishing qi,regulating qi to harmonize the stomach,and resolving phlegm to alle-viate stuffiness.By reviewing clinical and mechanistic studies on Xiangsha Liujunzi decoction in treating FD,this paper summa-rizes its efficacy.Clinical research demonstrates that modified single-formula treatment,combined formula therapy,integration with Western medicine,or adjunctive external therapies using Xiangsha Liujunzi decoction significantly improve FD symptoms.Mechanistic studies reveal its multi-target actions:regulating gastrointestinal motility,reducing visceral hypersensitivity,repai-ring the mucosal barrier,and modulating gut microbiota.This review discusses both clinical applications and mechanisms of Xiangsha Liujunzi decoction in FD treatment,aiming to explore recent advancements and provide novel insights and evidence for clinical diagnosis and management.关键词
香砂六君子汤/功能性消化不良/研究进展Key words
Xiangsha Liujunzi decoction/Functional dyspepsia/Review分类
医药卫生引用本文复制引用
聂峰,高松林,陈竣桦,邓澳林,刘沛恬,张子晨,朱明源,黄贵华..香砂六君子汤治疗功能性消化不良的研究进展[J].实用中医内科杂志,2026,40(4):45-49,5.基金项目
国医大师黄瑾明学术思想与临床诊疗传承发展研究中心建设项目(桂中医大党[2022]24号) （桂中医大党[2022]24号）
广西科技基地和人才专项(桂科AD19245168) （桂科AD19245168）
广西研究生教育创新计划项目(YCBZ2023148) （YCBZ2023148）
黄贵华桂派中医大师传承工作室项目(桂中医药科教发[2024]1号) （桂中医药科教发[2024]1号）
黄贵华广西名中医传承工作室项目(桂卫中医发[2017]2号) （桂卫中医发[2017]2号）
