同位素2026，Vol.39Issue(1)：72-83,12.DOI:10.7538/tws.2025.youxian.044
生物与环境中碳纳米材料稳定性同位素13C标记示踪应用进展
Quantitative Tracking of Carbon Nanomaterials in Biological and Environmental Systems:Advances in 13C Stable Isotope Labeling Technology
摘要
Abstract
Carbon nanomaterials(fullerenes,graphene,carbon nanotubes,etc.)have broad application prospects in the biomedical and environmental fields due to their unique physicochemical properties.However,the research on the migration,transformation,and toxicity assessment of these materials in ecosystems and organisms is challenged by the interference of complex environmental matrices.The 13C labeling technique,with its advantages of high sensitivity,non-radioactivity,and no interference with the intrinsic properties of materials,has become an important tool in the study of nano-biological effects and safety.This article systematically reviews the application of 13C labeling technology in quantitatively tracking the migration process of carbon nanomaterials in animals,intestinal microorganisms,plants,and aquatic ecosystems.Meanwhile,it introduces the 13C skeleton labeling schemes of carbon nanomaterials and the exploration of their synthesis mechanisms.Additionally,this article summarizes the main challenges currently faced by this technology and looks forward to its future development trends.关键词
稳定性同位素标记/碳纳米材料/纳米生物效应/环境生态安全/代谢示踪Key words
stable isotope labeling/carbon nanomaterials/nano-biological effects/environmental ecological safety/metabolic tracing分类
能源科技引用本文复制引用
王香利,张平,陈鹏,徐桂清,常雪灵..生物与环境中碳纳米材料稳定性同位素13C标记示踪应用进展[J].同位素,2026,39(1):72-83,12.基金项目
国家自然科学基金面上(12475298、11675189、11475194) （12475298、11675189、11475194）
国家重点研发计划(2021YFA1200904) （2021YFA1200904）
北京市自然科学基金面上(2202065、2152038) （2202065、2152038）
依托中国科学院北京同步辐射装置的建制化科研平台 （）
