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STAT3在子宫内膜癌中作用的研究进展

张筱雯 焦桢

妇儿健康导刊2026,Vol.5Issue(7):15-19,5.
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妇儿健康导刊2026,Vol.5Issue(7):15-19,5.DOI:10.3969/j.issn.2097-115X.2026.07.003

STAT3在子宫内膜癌中作用的研究进展

Research progress on the role of STAT3 in endometrial cancer

张筱雯 1焦桢2

作者信息

  • 1. 新疆医科大学研究生学院,新疆 乌鲁木齐 830054
  • 2. 新疆维吾尔自治区人民医院妇科,新疆 乌鲁木齐 830001
  • 折叠

摘要

Abstract

Endometrial cancer is one of the most threatening malignant tumors in the female reproductive system,with a continuous global rise in its incidence rate.Recent studies have revealed that the abnormal activation of STAT3 can promote the malignant progression of endometrial cancer through various pathways and mechanisms.This finding holds significant clinical translation value and research prospects,and has positive implications for delaying disease progression and improving treatment efficacy.However,the specific molecular mechanisms of STAT3 in the development and progression of endometrial cancer remain to be systematically elucidated.Therefore,in-depth exploration of STAT3's role in tumor cell proliferation and invasion,immune microenvironment regulation,angiogenesis,ferroptosis,and energy metabolism will provide theoretical support and novel intervention strategies for achieving precise targeted therapy for endometrial cancer.

关键词

子宫内膜癌/STAT3/分子机制/调控

Key words

Endometrial cancer/STAT3/Molecular mechanism/Regulation

分类

医药卫生

引用本文复制引用

张筱雯,焦桢..STAT3在子宫内膜癌中作用的研究进展[J].妇儿健康导刊,2026,5(7):15-19,5.

基金项目

新疆维吾尔自治区自然科学基金资助项目(2023D01C65). (2023D01C65)

妇儿健康导刊

2097-115X

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