武警医学2026，Vol.37Issue(4)：316-320,326,6.
MRI影像组学对无强化弥漫性胶质瘤术后5年复发的预测价值
Predictive value of MRI-based radiomics for 5-year postoperative recurrence of non-en-hancing diffuse gliomas
陆静 1孙婷 2王贵生 3吴春楠 3刘亚欧2
作者信息
- 1. 100070,首都医科大学附属北京天坛医院放射科||100039 北京,解放军总医院第三医学中心放射科
- 2. 100070,首都医科大学附属北京天坛医院放射科
- 3. 100039 北京,解放军总医院第三医学中心放射科
- 折叠
摘要
Abstract
Objective To investigate the value of the MRI-based radiomics model in predicting the recurrence of non-enhan-cing diffuse gliomas within 5 years after surgery.Methods A retrospective analysis was conducted on 116 patients with pathologically confirmed non-enhanced diffuse gliomas treated at Beijing Tiantan Hospital Affiliated to Capital Medical University from June 2016 to June 2020.Clinical pathological data,MRI images,and follow-up information were collected.Radiomics features and tumor location features were extracted using Python pyradiomics and Atlasquery tools.The LASSO algorithm was applied for feature dimensionality re-duction and selection.Five predictive models were constructed as follows:Model-1(Sex and Age),Model-2(Tumor Location),Mod-el-3(Radiomics),Model-4(Tumor Location+Radiomics),and Model-5(Sex+Age+Tumor Location+Radiomics).Receiver operat-ing characteristic(ROC)curves and decision curve analysis(DCA)were plotted to evaluate the predictive performance of the models.Results The areas under the ROC curve(AUC)for predicting postoperative recurrence were 0.529(Model-1),0.680(Model-2),0.912(Model-3),0.911(Model-4),and 0.917(Model-5),respectively.Model-5 demonstrated the best performance,achieving a sensitivity of 0.837,specificity of 0.866,and accuracy of 0.863,respectively in the test set.Conclusions The MRI radiomics-based model has high clinical value in predicting recurrence of non-enhancing diffuse gliomas within 5 years after surgery.关键词
胶质瘤/复发/磁共振成像/影像组学/预测价值Key words
glioma/recurrence/magnetic resonance imaging/radiomics/predictive value分类
医药卫生引用本文复制引用
陆静,孙婷,王贵生,吴春楠,刘亚欧..MRI影像组学对无强化弥漫性胶质瘤术后5年复发的预测价值[J].武警医学,2026,37(4):316-320,326,6.
