新疆环境保护2026，Vol.48Issue(1)：10-21,12.
青霉素降解菌的筛选鉴定及其降解特性研究
Study on the Screening,Identification,and Degradation Characteristics of Penicillin-degrading Bacteria
摘要
Abstract
Five penicillin-resistant strains were isolated and screened from the soil applied with penicillin residue organic fertilizer from a pharmaceutical factory,and their penicillin degradation efficiency was determined.One penicillin-efficient degrading bacterium was selected to study its morphology,physiological and biochemical characteristics and biosafety.The results showed that strain 127-1(Bacillus wiedmannii,NR_152692.1),a highly efficient penicillin-degrading bacterium,was identified as Bacillus wiedmannii by 16S rDNA sequence molecular identification.The degradation rate of penicillin with high concentration(1000 μg/mL)by strain 127-1 was as high as 99.93%within 48 hours.Strain 127-1could grow at 4～45℃,and the optimum growth conditions were pH=8.0 and salinity<3%.In addition,strain 127-1 has good growth-promoting functional characteristics and strong environmental adaptability,showing excellent application potential.关键词
青霉素/抗生素/降解菌/威德曼芽孢杆菌Key words
Penicillin/antibiotics/degrading bacteria/Bacillus wiedmannii分类
资源环境引用本文复制引用
李旭东,张洁,易鸳鸯,巴哈迪尔·麦麦提吾麦尔..青霉素降解菌的筛选鉴定及其降解特性研究[J].新疆环境保护,2026,48(1):10-21,12.基金项目
新疆维吾尔自治区重点研发项目(2020B03005-2) （2020B03005-2）
