湖北科技学院学报（医学版）2026，Vol.40Issue(2)：179-184,6.DOI:10.16751/j.cnki.2095-4646.2025091614
熊果苷抗肿瘤作用机制研究进展
Research Progress on the Mechanisms Underlying the Antitumor Effects of Arbutin
摘要
Abstract
Arbutin is a natural phenolic glycoside widely found in various plants and exhibits antioxidant,anti-inflammatory,and antitumor effects.In recent years,research on the antitumor effects of arbutin has become increasingly extensive,focusing on mechanisms such as inducing apoptosis in tumor cells,counteracting oxidative stress,inhibiting tumor cell proliferation and migration,regulating signaling pathways,and promoting cellular senescence.These findings suggest that arbutin holds potential as an antitumor agent.However,despite the identification of multiple biological activities of arbutin,the mechanisms underlying its antitumor effects remain contentious.This article provides a comprehensive review of the research progress on the antitumor mechanisms of arbutin,aiming to further explore its potential and mechanisms in cancer therapy,offer insights for future clinical translation studies,and promote the application of arbutin in antitumor treatments.关键词
熊果苷/抗肿瘤/细胞增殖/氧化应激Key words
Arbutin/Antitumor/Cell proliferation/Oxidative stress分类
医药卫生引用本文复制引用
梁嘉伟,王寒,王森,汪慧,阮英..熊果苷抗肿瘤作用机制研究进展[J].湖北科技学院学报（医学版）,2026,40(2):179-184,6.基金项目
湖北省教育厅科学研究计划项目(B2023165) （B2023165）
湖北省大学生创新创业项目(S202310927034) （S202310927034）
