亚太传统医药2026，Vol.22Issue(5)：71-76,6.DOI:10.11954/ytctyy.202605012
菟丝子酊的提取工艺优化
Optimization of the Extraction Process of Cuscutae Semen Tincture
摘要
Abstract
Objective:Optimize the extraction process of Cuscutae Semen Tincture.Methods:Taking the contents(mg/g)of hyperoside,isorhamnetin,astragalin,and kaempferol as evaluation indicators,the entropy weight method was used to determine the weight coefficients,and the comprehensive score of multiple indicators was calculated.Based on the single-factor test,taking the soaking time(days),the ratio of material to liquid(g/mL),and the ethanol concentration(%)as factors were investigated by the Box-Behnken response surface method to optimize the extraction process of Cuscutae Semen Tincture.Results:The optimal extraction process of Cuscutae Semen Tincture was to soak the fine powder of Cuscutae Semen in 90%ethanol at a ratio of material to liquid of 1∶5(g/mL)for 7 days.The results of process verification showed that the extracted contents(mg/g)of hyperoside,isorhamnetin,astragalin,kaempferol were 2.306 6,0.474 7,0.587 7,0.148 1 respectively,and the comprehensive score was 98.64.Conclusion:The opti-mized process is reasonable,stable and reliable,which can provide a basic basis for the extraction process of Cuscutae Semen Tincture.关键词
菟丝子酊/提取工艺/Box-Behnken/熵权法Key words
cuscutae semen tincture/extraction process/box-behnken/entropy weight method分类
医药卫生引用本文复制引用
蔡沓栗,于虹敏,黄绍华,全玉妹..菟丝子酊的提取工艺优化[J].亚太传统医药,2026,22(5):71-76,6.基金项目
福州市卫生健康系统科技计划项目(2023-S-wq11) （2023-S-wq11）
福建中医药大学校管课题(X2022012) （X2022012）
