医学信息2026，Vol.39Issue(7)：41-49,9.DOI:10.3969/j.issn.1006-1959.2026.07.008
基于数据挖掘分析中药复方保肝护肝的用药规律
Medication Rules Analysis of Traditional Chinese Medicine Compound for Hepatoprotection Based on Data Mining
摘要
Abstract
Objective To explore the medication rules of traditional Chinese medicine compounds for hepatoprotection,and to provide a scientific basis for the development of hepatoprotective products.Methods The literature was retrieved from databases including China National Knowledge Infrastructure(CNKI),WANFANG DATA,VIP,SinoMed,and others until July 25,2024.The keywords such as"liver injury""alcoholic liver"and"hepatoprotection"were searched,relevant literatures were collected,traditional Chinese medicine compounds were screened,and an effective database was established.The frequency and dose distribution of Chinese herbs were statistically analyzed.The core drugs in the compound were identified by high-frequency Chinese medicine factor analysis,cluster analysis and related rule analysis,to study the medication rules of Chinese medicine compound for hepatoprotection.Results A total of 143 prescriptions were collected,involving 239 Chinese herbs with a total frequency of 1399 times,of which 39 herbs were used more than 10 times,and the most frequently used was Poria,with a utilization rate of 46.15%.The overall dosage of Poria,Radix Puerariae,virgate wormwood herb and Fructus Crataegi were relatively high,while that of Radix et Rhizoma Glycyrrhizae was relatively low.Chinese herbs such as Poria,Radix et Rhizoma Glycyrrhizae and Radix Puerariae were often used in combination with each other in the treatment prescription,they were the core of the traditional Chinese medicine compound for hepatoprotection.Conclusion Data mining reveals the pattern of drug use and dosage of traditional Chinese medicine compound with Poria,Radix et Rhizoma Glycyrrhizae,Radix Puerariae and Semen Hoveniae as the core compatibility,and provides theoretical support and scientific basis for the development of traditional Chinese medicine compound for hepatoprotection.关键词
保肝/中药复方/数据挖掘/用药规律Key words
Hepatoprotection/Traditional Chinese medicine compound/Data mining/Medication rule分类
医药卫生引用本文复制引用
高雷雷,徐志成..基于数据挖掘分析中药复方保肝护肝的用药规律[J].医学信息,2026,39(7):41-49,9.基金项目
安徽省现代中药产业共性技术研究中心开放课题(编号:AHTCMGTRC-2023-03) （编号:AHTCMGTRC-2023-03）
