医学信息2026，Vol.39Issue(8)：103-108,6.DOI:10.3969/j.issn.1006-1959.2026.08.018
健脾益肾祛瘀法联合穴位贴敷对糖尿病肾病(G3A2期)合并骨质疏松症的临床疗效
Clinical Effect of Jianpi Yishen Quyu Method Combined with Acupoint Application on Diabetic Nephropathy(G3A2 Stage)Complicated with Osteoporosis
摘要
Abstract
Objective To analyze the clinical efficacy of Jianpi Yishen Quyu method combined with acupoint application in patients with diabetic nephropathy(G3A2 stage)complicated with osteoporosis.Methods A total of 94 patients with diabetic kidney disease(stage G3A2)complicated by osteoporosis,who were treated at Jiujiang Hospital of Traditional Chinese Medicine from January to October 2024,were selected as the study subjects.They were divided into a control group and a treatment group using a random number table method,with 47 patients in each group.Both groups received conventional basic treatment.On this basis,the control group was treated with calcium carbonate and vitamin D3 tablets combined with calcitriol soft capsules,while the treatment group was additionally treated with Jianpi Yishen Quyu method and acupoint application.The clinical efficacy,serum indicator levels[serum calcium,serum phosphorus,alkaline phosphatase(ALP),25-hydroxyvitamin D],bone mineral density[lumbar spine(L1~L4),femoral neck],traditional Chinese medicine syndrome scores,and the incidence of adverse reactions(hypoglycemia,diarrhea,headache,rash)were compared between the two groups.Results Compared with the total effective rate of the control group(76.60%),the treatment group was higher,reaching 95.74%(P＜0.05).After treatment,the levels of serum calcium,25-hydroxyvitamin D and bone mineral density of femoral neck and lumbar spine(L1-L4)in the treatment group were higher than those in the control group,while the levels of serum phosphorus and ALP were lower than those in the control group(P＜0.05).After treatment,the scores of traditional Chinese medicine syndrome(main symptom and secondary symptom)in the treatment group were lower than those in the control group(P＜0.05).Compared with the control group(17.02%),the incidence of adverse reactions in the treatment group was lower,only 4.26%(P＜0.05).Conclusion Jianpi Yishen Quyu method combined with acupoint application has a definite clinical effect in the treatment of patients with diabetic nephropathy(G3A2 stage)complicated with osteoporosis,which can improve the serum calcium,25-hydroxyvitamin D level and bone mineral density,reduce the serum phosphorus and ALP levels,and relieve the clinical symptoms of patients,with high safety.关键词
健脾益肾祛瘀法/穴位贴敷/糖尿病肾病/骨质疏松症Key words
Jianpi Yishen Quyu method/Acupoint application/Diabetic nephropathy/Osteoporosis分类
医药卫生引用本文复制引用
王静巍,陈鑫成,朱红霞,周文娣,余敏锋..健脾益肾祛瘀法联合穴位贴敷对糖尿病肾病(G3A2期)合并骨质疏松症的临床疗效[J].医学信息,2026,39(8):103-108,6.基金项目
江西省中医药管理局科技计划项目(编号:202410678) （编号:202410678）
