摘要
Abstract
Objective To explore the effect of modified Danggui Shaoyao powder on the total effective rate and quality of life of female post adolescent acne(FPAA).Methods From June 2022 to June 2024,a total of 60 patients with FPAA who were admitted to Longnan Hospital of Traditional Chinese Medicine were selected as the study subjects and randomly assigned,by means of a lottery method,into a conventional group(30 patients)and a traditional Chinese medicine group(30 patients).The conventional group was treated with isotretinoin soft capsules alone,whereas the traditional Chinese medicine group received a modified Danggui Shaoyao powder on the basis of the same treatment.Comparisons were made between the two groups in terms of treatment efficacy,TCM symptom scores(including facial flushing,papule-pustule heat sensation,and skin greasiness),the Global Acne Grading System(GAGS)score,the Dermatology Life Quality Index(DLQI)score,as well as recurrence rate and adverse reactions.Results In terms of the total response rate,the traditional Chinese medicine group demonstrated a significantly higher rate compared with the conventional group(P＜0.05).After treatment,the scores of TCM symptoms(facial flushing,papule-pustule heat sensation,skin greasiness)in the two groups were lower than those before treatment,and the scores of TCM symptoms(facial flushing,papule-pustule heat sensation,skin greasiness)in the traditional Chinese medicine group were lower than those in the conventional group(P＜0.05).After treatment,the GAGS and DLQI scores of the two groups were lower than those before treatment,and the GAGS and DLQI scores of the traditional Chinese medicine group were lower than those of the conventional group(P＜0.05).At 3 months after treatment,the recurrence rate in the traditional Chinese medicine group was found to be significantly lower than that in the conventional group(P＜0.05).In contrast,no statistically significant difference was observed between the two groups in terms of the incidence of adverse reactions(P＞0.05).Conclusion Modified Danggui Shaoyao powder is effective in the treatment of FPAA,which can improve the total effective rate,reduce the symptoms of TCM and the severity of acne,and has a positive effect on the quality of life,with good safety and low recurrence rate.关键词
女性青春期后痤疮/当归芍药散加减方/中医症状/生活质量Key words
Female post adolescent acne/Modified Danggui Shaoyao powder/TCM symptoms/Quality of life分类
医药卫生
