临床研究2026，Vol.34Issue(4)：8-12,5.DOI:10.12385/j.issn.2096-1278(2026)04-0008-05
不同分度宫腔粘连患者宫腔镜术后辅助人工周期治疗的疗效及影响因素研究
Efficacy and Influencing Factors of Postoperative Adjuvant Artificial Cycle Therapy After Hysteroscopy in Patients with Different Degrees of Intrauterine Adhesions
摘要
Abstract
Objective To investigate the clinical outcomes and influencing factors of patients with different degrees of intrauterine adhesions(IUA)under a degree-based stratified artificial cycle therapy regimen.Methods A total of 86 patients with IUA admitted to Henan Provincial People's Hospital from June 2022 to June 2025 were selected.All patients underwent hysteroscopic adhesiolysis and received postoperative artificial cycle therapy.According to the IUA grading criteria,the patients were divided into a mild group(32 cases),a moderate group(37 cases),and a severe group(17 cases).The treatment response rate,menstrual recovery,improvement in uterine cavity volume,and incidence of complications were compared among the three groups,and the factors influencing treatment efficacy were analyzed.Results The treatment response rate was 93.75%in the mild group,72.97%in the moderate group,and 47.06%in the severe group,and the difference among the three groups was statistically significant(P＜0.05).The rate of return to normal menstruation in the mild group was higher than that in the severe group.The postoperative endometrial thickness and the improvement in uterine cavity volume in the mild group were both higher than those in the moderate group and the severe group,and those in the moderate group were both higher than those in the severe group;the differences were all statistically significant(P＜0.05).There was no statistically significant difference in the incidence of complications among the three groups(P＞0.05).Univariate analysis showed that IUA grade,preoperative uterine cavity volume,and postoperative medication adherence were associated with treatment efficacy(P＜0.05).Multivariate Logistic regression analysis showed that severe IUA(OR=5.924,95%CI:1.789-19.693,P=0.003)and poor postoperative medication adherence(OR=5.368,95%CI:1.795-16.052,P=0.002)were independently associated with treatment failure.Conclusion Under the degree-based postoperative adjuvant artificial cycle regimen adopted at this center,recovery outcomes differ among patients with different degrees of IUA.Severe IUA and poor postoperative medication adherence are independent factors associated with treatment efficacy.关键词
宫腔粘连/宫腔镜手术/人工周期治疗/分度/疗效/影响因素Key words
intrauterine adhesions/hysteroscopic surgery/artificial cycle therapy/grading/efficacy/influencing factors引用本文复制引用
刘梁,杜晗,张潇月,靳君丽,刘广芝..不同分度宫腔粘连患者宫腔镜术后辅助人工周期治疗的疗效及影响因素研究[J].临床研究,2026,34(4):8-12,5.基金项目
2023年度国家卫生健康委科学研究基金—河南省医学科技攻关计划省部共建项目(SBGJ202302012). （SBGJ202302012）
