Pseudorabies virus TK protein antagonizes alpha interferon response by interfering with the JAK1-STAT1 interaction
Jingjing Song Jun Tang Pinghuang Liu Changyong Cheng Jin Yuan Rui Zhang Rulan Bai Dongyue Xing Chuang Li Xuan Chen Feiyang Zheng Mingyi Lei Yujin Wang Yuxin Liu
中国病毒学2026,Vol.41Issue(1):132-143,12.
中国病毒学2026,Vol.41Issue(1):132-143,12.DOI:10.1016/j.virs.2026.01.004
Pseudorabies virus TK protein antagonizes alpha interferon response by interfering with the JAK1-STAT1 interaction
Pseudorabies virus TK protein antagonizes alpha interferon response by interfering with the JAK1-STAT1 interaction
摘要
关键词
Pseudorabies virus(PRV)/Thymidine kinase(TK)/IFN signaling pathway/STAT1/JAK1Key words
Pseudorabies virus(PRV)/Thymidine kinase(TK)/IFN signaling pathway/STAT1/JAK1引用本文复制引用
Jingjing Song,Jun Tang,Pinghuang Liu,Changyong Cheng,Jin Yuan,Rui Zhang,Rulan Bai,Dongyue Xing,Chuang Li,Xuan Chen,Feiyang Zheng,Mingyi Lei,Yujin Wang,Yuxin Liu..Pseudorabies virus TK protein antagonizes alpha interferon response by interfering with the JAK1-STAT1 interaction[J].中国病毒学,2026,41(1):132-143,12.基金项目
This work was supported by the National Natural Science Foundation of China(32172829 and 32192453),the Beijing Municipal Natural Science Foundation(6232026),the State Key Laboratory of Veterinary Public Health and Safety(grant number 2025SKLVPHS07)and the 2115 Talent Development Program of China Agricultural University. (32172829 and 32192453)