中国工程科学2026，Vol.28Issue(2)：159-169,11.DOI:10.15302/J-SSCAE-2025.06.038
合成生物学驱动的新材料创新研究
Synthetic Biology-Driven Innovation in Advanced Materials
摘要
Abstract
Synthetic biology is emerging as a frontier interdisciplinary discipline that is increasingly regarded as a key driver of sustainable innovation in advanced materials.By leveraging the design-build-test-learn(DBTL)cycle and through genetic circuit reconstruction,metabolic pathway optimization,and enzyme engineering,predictable and programmable microbial cell factories are being created,enabling bio-based material production.This study summarizes the technological foundations that underpin synthetic biology in material innovation,with a focus on elucidating the mechanisms of novel material synthesis in microbial cell factories,the advantages of biosynthetic approaches,and the functional roles of key biological elements in material production.On this basis,it highlights representative applications in bio-based,smart,functional,and biodegradable materials,and discusses how synthetic biomanufacturing is reshaping the green and intelligent transformation of the materials sector.Finally,it outlines future development trends and proposes development strategies.Future progress will rely on closer interdisciplinary integration,more rapid translation into industrial practice,and the development of platform-based and modular strategies,which together will support the carbon neutrality goals and the high-quality growth of the materials industry.关键词
合成生物学/微生物细胞工厂/新材料/生物基材料Key words
synthetic biology/microbial cell factory/advanced materials/bio-based materials分类
化学化工引用本文复制引用
朱孟宇,戈钧,黄海霞,张闳肆..合成生物学驱动的新材料创新研究[J].中国工程科学,2026,28(2):159-169,11.基金项目
中国工程院咨询项目"我国化工新材料绿色低碳发展战略研究"(2024-XBZD-09) （2024-XBZD-09）
国家重点研发计划项目(2023YFA0913600) （2023YFA0913600）
国家自然科学基金项目(22425803) Chinese Academy of Engineering project"Green and Low-Carbon Development Strategies of Chemical New Materials in China"(2024-XBZD-09) （22425803）
National Key Research and Development Program of China(2023YFA0913600) （2023YFA0913600）
The National Natural Science Foundation of China Project(22425803) （22425803）
