局解手术学杂志2026，Vol.35Issue(4)：294-298,5.DOI:10.11659/jjssx.04E025014
全膝关节置换术后腰椎和髋部骨密度与人工关节无菌性松动的关系
Association between lumbar and hip bone mineral density after total knee arthroplasty and aseptic loosening of the prosthesis
摘要
Abstract
Objective To investigate the changes in lumbar and hip bone mineral density in patients after total knee arthroplasty(TKA),and the correlation between bone mineral density changes and aseptic loosening(AL)of the prosthesis in TKA patients was analyzed.Methods A total of 302 patients who underwent TKA in our hospital from August 2017 to July 2020 were enrolled.They were divided into the AL group(31 cases)and the non-AL group(271 cases)according to the occurrence of prosthesis AL at 3 months postoperatively.All patients were followed up for 3 years,and the changes in lumbar and hip bone mineral density before and after surgery were compared between the two groups.Results Compared with preoperative values,bone mineral density of L2,L3 and L4 were significantly decreased at 1,2 and 3 years after surgery in the AL group(P<0.05).In the non-AL group,bone mineral density of L2 was significantly increased at 1 and 3 years after surgery compared with preoperative values(P<0.05),and bone mineral density of L3 was significantly increased at 2 and 3 years after surgery compared with preoperative values(P<0.05).Moreover,bone mineral density of L2,L3 and L4 in the AL group were significantly lower than those in the non-AL group at 1,2 and 3 years after surgery(P<0.05).In the AL group,bone mineral density of the femoral neck and greater trochanter were significantly decreased at 1,2 and 3 years after surgery compared with preoperative values(P<0.05).In the non-AL group,bone mineral density of the femoral neck was significantly increased at 3 years after surgery compared with preoperative values(P<0.05),and bone mineral density of the greater trochanter were significantly increased at 1,2 and 3 years after surgery compared with preoperative values(P<0.05).Moreover,bone mineral density of the femoral neck and greater trochanter in the AL group were significantly lower than those in the non-AL group at 1,2 and 3 years after surgery(P<0.05).Conclusion Patients with AL after TKA have significantly decreased bone mineral density of the lumbar spine and hip,and AL is negatively correlated with lumbar and hip bone mineral density.关键词
全膝关节置换术/腰椎/髋部/骨密度/人工关节/无菌性松动Key words
total knee arthroplasty/lumbar/hip/bone mineral density/prosthesis/aseptic loosening分类
医药卫生引用本文复制引用
尹识渊,黄朝明,裴儒,何仁豪,张杰..全膝关节置换术后腰椎和髋部骨密度与人工关节无菌性松动的关系[J].局解手术学杂志,2026,35(4):294-298,5.基金项目
宿迁市科研计划项目(Z2024082) （Z2024082）
