中国临床医学影像杂志2026，Vol.37Issue(4)：229-232,4.DOI:10.12117/jccmi.2026.04.001
基于低频振幅和局部一致性的遗尿症儿童认知功能障碍的静息态脑功能成像研究
Resting-state brain functional imaging of cognitive dysfunction in children with enuresis based on amplitude of low-frequency fluctuations and regional homogeneity
摘要
Abstract
Objective:To explore the relationship between ALFF and ReHo of whole brain voxels in resting-state brain functional imaging and the occurrence and development of cognitive dysfunction in children with enuresis.Methods:From June 2019 to June 2021,24 children with enuresis complicated with cognitive impairment(study group)and 24 healthy chil-dren(control group)were selected.The children in both groups were examined by MRI.The differences in resting-state brain function,ReHo,ALFF brain images and cognitive function were compared between two groups,and the correlation between imaging indexes and cognitive function was analyzed in all subjects.Results:The MMSE and MoCA scores of two groups had statistical significance,and the MMSE and MoCA scores of study group were obvious lower than control group(P＜0.05).The ALFF values of the left talus gyrus and the right talus gyrus in the study group were significantly lower than those in the control group(P＜0.05).The ReHo values of the left talus gyrus,left middle occipital gyrus,bilateral lingual gyrus,right wedge lobe,right fusiform gyrus and right superior occipital gyrus in the study group were significantly lower than those in the con-trol group(P＜0.05).Pearson correlation analysis in all 48 subjects showed that ALFF values in the left calcarine gyrus and the right calcarine gyrus were positively correlated with MMSE,and ReHo values in the left middle occipital gyrus and right su-perior occipital gyrus were positively correlated with MoCA(P＜0.05).Conclusion:The resting-state brain functional imaging abnormalities of the left talar gyrus,right talar gyrus,left middle occipital gyrus and right supraoccipital gyrus in children with enuresis are correlated with the occurrence and development of cognitive dysfunction.关键词
夜间遗尿症/磁共振成像Key words
Nocturnal Enuresis/Magnetic Resonance Imaging分类
医药卫生引用本文复制引用
王雅韵,刘卓,庄雄,刘良卿..基于低频振幅和局部一致性的遗尿症儿童认知功能障碍的静息态脑功能成像研究[J].中国临床医学影像杂志,2026,37(4):229-232,4.基金项目
江苏省脑病生物信息重点实验室开放资助项目,编号:XZSYSKF2023026 （）
常州市卫健委临床前沿技术,编号:QY202409. （）
