中国全科医学2026，Vol.29Issue(17)：2425-2432,8.DOI:10.12114/j.issn.1007-9572.2024.0289
中性粒细胞外陷阱在胃癌中的研究进展
Research Progress of Neutrophil Extracellular Traps in Gastric Cancer
摘要
Abstract
In recent years,neutrophil extracellular traps(NETs)have garnered increasing attention in cancer research,particularly regarding their mechanisms and clinical significance in gastric cancer.This paper systematically and comprehensively explores the research progress of NETs in gastric cancer,including the formation mechanisms of NETs,their role in the gastric cancer microenvironment,and their impact on the occurrence,development,and metastasis of gastric cancer.By reviewing relevant literature,the paper summarizes the crucial roles of NETs in gastric cancer immune evasion,inflammatory response,and interactions with other tumor cells.The paper indicates that NETs not only promote the proliferation and metastasis of tumor cells during the occurrence and progression of gastric cancer but are also closely associated with poor prognosis in gastric cancer patients.Additionally,NETs affect the treatment outcomes of gastric cancer by inducing an immunosuppressive environment and enhancing cancer cell drug resistance.This paper provides a reference for the diagnosis and treatment of gastric cancer and offers insights for further research on NETs in gastric cancer.关键词
胃癌/中性粒细胞外陷阱/胃癌转移/作用机制/综述Key words
Gastric cancer/Neutrophil extracellular traps/Gastric cancer metastasis/Mechanism of action/Review分类
医药卫生引用本文复制引用
马晓雨,马晓梅,武国智,郑亚,郭庆红..中性粒细胞外陷阱在胃癌中的研究进展[J].中国全科医学,2026,29(17):2425-2432,8.基金项目
甘肃省联合科研基金重大项目(23JRRA1487) （23JRRA1487）
甘肃省卫生健康行业科研项目(GSWSQN2023-02) （GSWSQN2023-02）
