中国比较医学杂志2026，Vol.36Issue(7)：114-124,11.DOI:10.3969/j.issn.1671-7856.2026.07.010
耳穴疗法通过调控神经生物学缓解卒中后抑郁的机制研究进展
Research progress on the mechanism by which auricular therapy alleviates post-stroke depression through regulating neurobiology
摘要
Abstract
Post-stroke depression(PSD)is the most common mental complication after stroke,seriously affecting recovery of neurological function and quality of life.Although antidepressants are currently the first-line treatment,they have limitations such as cardiotoxicity,gastrointestinal reactions,and relatively high costs.As a non-pharmaceutical intervention method integrating traditional Chinese medicine and modern neuroanatomy,auricular therapy has shown unique advantages in PSD treatment through a multi-target regulatory mechanism.From the perspective of neurobiology,this article systematically reviews the mechanism of auricular therapy in PSD intervention,including:(1)the regulation of monoamine and amino acid neurotransmitter homeostasis;(2)promoting neural plasticity and the reorganization of brain network functions;(3)inhibiting neuroinflammation and oxidative stress responses;(4)and regulating the neuroendocrine system.This review aims to comprehensively explain the mechanism by which auricular therapy alleviates PSD through a multidimensional neuro-immune-endocrine regulatory network to promote further research and application in PSD treatment.关键词
耳穴疗法/卒中后抑郁/神经生物学/机制Key words
auricular therapy/post-stroke depression/neurobiology/mechanism分类
医药卫生引用本文复制引用
先容,杨智鹏,王超,王甜,林征玉,刘海静..耳穴疗法通过调控神经生物学缓解卒中后抑郁的机制研究进展[J].中国比较医学杂志,2026,36(7):114-124,11.基金项目
云南省科技厅科技计划项目(202401AZ070001-018,202405AS350007). （202401AZ070001-018,202405AS350007）
