中国斜视与小儿眼科杂志2026，Vol.34Issue(1)：1-6,后插13,7.DOI:10.3969/J.ISSN.1005-328X.2026.01.001
学龄期儿童配戴多元透镜分区离焦镜片后眼轴和屈光度变化的对照研究
A comparative study on axial length and refractive error changes in school-age children wearing diversified seg-mental defocus optimization lens
摘要
Abstract
Objective To investigate the differences in axial length and refractive error changes between school-age children wearing a Diversified Segmental Defocus Optimization(DSDO)lens and those using conventional optical correc-tion,across different baseline refractive groups.Methods This prospective non-randomized controlled study enrolled school-age children with a spherical equivalent(SE)ranging from-2.00D to+2.00D.Based on participant and parental preference,children were assigned to either the control group(physiological hyperopes without correction or low myopes wearing single-vision spectacles)or the experimental group(wearing the DSDO lens).According to cycloplegic retinos-copy results,participants were stratified into three refractive subgroups:1)Low hyperopia:+0.75D＜SE≤+2.00D;2)Pre-myopia:-0.50D＜SE≤+0.75D;3)Low myopia:-2.00D≤SE≤-0.50D.Follow-up examinations were con-ducted at 6 and 12 months after enrollment.Primary outcome measures included axial length(AL),SE,choroidal thick-ness(CHT),and choroidal vascularity index(CVI).Results A total of 113 participants completed the 12-month follow-up(attrition rate:3.4％).Axial elongation was significantly lower in all experimental subgroups compared to their respective control subgroups:low hyperopia(0.12±0.11 mm vs.0.21±0.09 mm;P=0.0003;Cohen's d=0.90),pre-myopia(0.18±0.19 mm vs.0.38±0.18 mm;P＜0.0001;d=1.08),and low myopia(0.22±0.22 mm vs.0.51±0.20 mm;P＜0.0001;d=1.36).Changes in SE followed a similar trend to AL.At the 6-month follow-up,CHT in all measured sectors was significantly thicker in the pre-myopia and low myopia experimental subgroups compared to controls.At 12 months,these differences persisted in most sectors for the pre-myopia subgroup and in all sectors for the low myopia subgroup.Significant CVI changes were primarily observed in the low hyperopia subgroup.Conclusions Wearing DSDO lenses was associated with slower axial elongation and myopia progression compared with conventional correction.关键词
离焦镜片/近视控制/近视预防/远视储备/眼轴/屈光度/学龄期儿童Key words
Defocus spectacles/Myopia control/Myopia prevention/Hyperopia reserve/Axial length/Refraction/School-aged children引用本文复制引用
许江涛,戈正妍,袁湘华,段宝莹,曹兴雨,陈小艳,吴阳..学龄期儿童配戴多元透镜分区离焦镜片后眼轴和屈光度变化的对照研究[J].中国斜视与小儿眼科杂志,2026,34(1):1-6,后插13,7.基金项目
爱尔眼科医院集团科研基金项目(AGK2303D06) （AGK2303D06）
昆明市卫健委卫生科研项目(2023-07-02-005) （2023-07-02-005）
