中国药科大学学报2026，Vol.57Issue(2)：189-195,7.DOI:10.11665/j.issn.1000-5048.2026012803
甘青乌头正丁醇部位苷类化学成分研究
Studies on glycosides from the n-butanol fraction of Aconitum tanguticum
摘要
Abstract
In order to investigate the chemical constituents of glycosides in Aconitum tanguticum(Maxim.)Stapf,column chromatographic techniques such as silica gel,ODS,Sephadex LH-20,and semi-preparative high performance liquid chromatography were used to afford eight glycosides from the n-butanol fraction of the 85％ethanol extract of Aconitum tanguticum.Based on the physicochemical properties and spectral data,these compounds were identified as N-4-O-(β-D-glucopyranosyl)-phenethylbenzamide(1),N-(2′-β-D-glucopyranosyl-5′-methoxysalicyl)-4-hydroxy-3-methoxyanthranilic acid methyl ester(2),N-(2′-β-D-glucopyranosyl-5′-hydroxysalicyl)-4-hydroxy-3-methoxyanthranilic acid methyl ester(3),salidroside(4),benzyl primeveroside(5),phenethanol-β-D-xylose-(1″→6′)-β-D-glucopyranoside(6),4-dihydroxyphenethoxy-8-O-β-D-[6-O-(4-O-β-D-glucopyranosyl)-feruloyl]-glucopyranoside(7),phenethanol-α-L-arabinopyranosyl-(1″→6′)-β-D-glucopyranoside(8).Among them,compounds 1 and 2 were new compounds,and compounds 5,6,8 were isolated from Aconitum tanguticum for the first time.关键词
甘青乌头/化学成分/苷类化合物/分离鉴定Key words
Aconitum tanguticum/chemical constituents/glycosides/isolation and identification分类
医药卫生引用本文复制引用
赵梦媛,方泗杨,李丹婷,李啟恩,潘珂,殷志琦..甘青乌头正丁醇部位苷类化学成分研究[J].中国药科大学学报,2026,57(2):189-195,7.基金项目
国家自然科学基金项目(No.U24A20351) （No.U24A20351）
江苏高校"青蓝工程"项目 This study was supported by the National Natural Science Foundation of China(No.U24A20351)and the Qing Lan Project of Jiangsu Higher Education Institutions and Science （No.U24A20351）
