中医临床研究2026，Vol.18Issue(2)：59-66,8.DOI:10.3969/j.issn.1674-7860.2026.02.009
动脉粥样硬化的中医证型、证素及用药规律分析
An analyses of TCM syndrome types,TCM elements and medication rules in patients with atherosclerosis
摘要
Abstract
Objective:To explore the medication rules of traditional Chinese medicine(TCM)prescriptions for treating atherosclerosis(AS)in Jiangxi Hospital of Traditional Chinese Medicine by using data mining technology,so as to provide references for optimizing clinical treatment approach.Methods:In the past ten years,the clinical data of AS patients treated in the outpatient,emergency and inpatient departments of Jiangxi Hospital of Traditional Chinese Medicine were collected.By using bibliometric methods,frequency analysis,and association rule analysis,the TCM syndrome types,syndrome element classifications,and medication rules of AS prescriptions were summarized.Results:In the study of TCM for AS,88 patients who met the inclusion and exclusion criteria were finally included.A total of 238 TCM prescriptions were involved.The most frequently used TCM were Fuling(Poria),Chenpi(Pericarpium Citri Reticulatae),Fabanxia(Rhizoma Pinelliae Praeparatum),etc.The distribution of drug natures and flavors was mainly cold and warm,bitter and sweet,and mostly belonged to the liver and lung meridians.The categories of TCM mainly included tonifying deficiency drugs,promoting blood circulation and removing blood stasis drugs,and heat-clearing drugs.Association rule analysis showed that Wuweizi(Fructus Schisandrae Chinensis)-Maidong(Radix Ophiopogonis),Dilong(Pheretima)-Chuanxiong(Rhizoma Ligustici Chuanxiong)were the couplet medicinals with the highest support degree,and Rougui(Cortex Cinnamomi)-Sigualuo(Retinervus Luffae Fructus)were the couplet medicinals with the highest lift.High-frequency prescriptions were Shengmai Yin combined with the Gualou Xiebai Banxia decoction(生脉饮合瓜蒌薤白半夏汤),the Xuefu Zhuyu decoction(血府逐瘀汤),Tianma Yin(天麻饮),etc.A total of 77 articles were ultimately included in the study on TCM syndrome types and elements,comprising 64 articles on syndrome types,with the highest proportions being phlegm-damp obstruction syndrome,phlegm-stasis interaction syndrome,and Qi(气)deficiency with blood stasis syndrome.Additionally,13 articles focused on TCM elements,with the top three being blood stasis,Qi deficiency,and phlegm-dampness turbidity.Conclusion:The TCM treatment ideas for AS are mainly promoting blood circulation and removing blood stasis,tonifying and regulating Qi,clearing heat and relieving exterior symptoms.High-frequency TCM and prescriptions mostly involve the effects of promoting blood circulation and dredging collaterals and nourishing and tonifying,which are closely related to the mechanism of AS with blood stasis blocking collaterals and deficiency in origin and excess in branch,and in line with the TCM treatment principles of AS.关键词
动脉粥样硬化/中药/证型/证素/用药规律Key words
Atherosclerosis/Traditional Chinese medicine/Syndrome type/Syndrome element/Medication rule分类
医药卫生引用本文复制引用
李勇,张德欣,方建和,邹玉雄,李靖怡,何媛,敖梅英,刘晓蒙,章莹,李靖焜,吴皎..动脉粥样硬化的中医证型、证素及用药规律分析[J].中医临床研究,2026,18(2):59-66,8.基金项目
江西省教育厅科学技术研究重点项目(GJJ211205) （GJJ211205）
江西省教育厅科技项目(GJJ211201) （GJJ211201）
江西中医药大学校级教改项目(2022jzyx-2) （2022jzyx-2）
国家自然科学基金项目(82060658) （82060658）
江西中医药大学博士启动基金项目(2018BSZR009). （2018BSZR009）
