中医临床研究2026，Vol.18Issue(2)：105-110,6.DOI:10.3969/j.issn.1674-7860.2026.02.016
基于伏风理论治疗免疫球蛋白A肾病的临床研究
Clinical study on the treatment of IgA nephropathy with the theory of"latent wind pathogen lodged in the body"
摘要
Abstract
Objective:This study aims to explore the guiding role of the latent wind pathogen lodged theory in the treatment of IgA nephropathy(IGAN).Building on the existing traditional Chinese medicine(TCM)etiology of IGAN,it further investigates whether latent wind pathogenis serve as a significant etiological factor in the chronic persistent stage of IGAN.Methods:By applying the method of conventional syndrome differentiation and treatment supplemented with wind-dispersing drugs,30 cases of IGAN in the chronic persistent stage were treated.It was observed whether the combination of conventional syndrome differentiation and wind-dispersing drugs could improve the efficacy of treating IGAN,and thus determine whether the internal accumulation of wind pathogens is an significant etiological factor of IGAN and whether the wind-dispersing method is an important method in TCM treatment of IGAN.Sixty cases of IGAN in the chronic persistent stage were selected and divided into an observation group and a control group,with 30 cases in each.30 cases in the chronic persistent stage in the observation group were treated with wind-dispersing drugs on the basis of conventional syndrome differentiation,while 30 cases in the control group were treated only with conventional syndrome differentiation without wind-dispersing drugs.After the treatment,the syndrome score,therapeutic effective rate,urinary red blood cell count,24-hour urinary protein excretion and glomerular filtration rate of the two groups were observed.Results:In terms of syndrome score,the observation group was marginally better than the control group,with no statistically significant difference(P>0.05),but in terms of total effective rate,urinary red blood cell count,24-hour urinary protein excretion and glomerular filtration rate,the observation group performed significantly better than the control group,with statistically significant differences(P<0.05).Conclusion:Wind pathogen lodged in the body is an important cause of chronic persistent stage of IGAN;the use of wind-dispersing drugs can significantly improve the efficacy in the treatment of IGAN,including symptom amelioration,and therapeutic effective rate and renal function improvement.关键词
风邪内伏/免疫球蛋白A肾病/祛风药/临床研究Key words
Latent wind pathogen/IgA nephropathy/Wind-dispersing drugs/Clinical research分类
医药卫生引用本文复制引用
肖媛,欧阳晃平..基于伏风理论治疗免疫球蛋白A肾病的临床研究[J].中医临床研究,2026,18(2):105-110,6.基金项目
江西省中医药科技计划项目(2020A0151). （2020A0151）
