中医临床研究2026，Vol.18Issue(8)：49-54,6.DOI:10.3969/j.issn.1674-7860.2026.08.010
附子山萸汤治疗慢性阻塞性肺疾病急性加重期痰浊阻肺证临床疗效观察
Clinical observation of Fuzi Shanyu Tang in treating AECOPD in patients with phlegm-turbidity obstructing the lung syndrome
摘要
Abstract
Objective:The present study aims to explore the role of Fuzi Shanyu Tang(附子山萸汤)in the treatment of phlegm-turbidity obstructing the lung syndrome in acute exacerbation of chronic obstructive pulmonary disease(AECOPD),as guided by the theory of Qi(气)movement.Methods:A total of 60 patients diagnosed with AECOPD of phlegm-turbidity obstructing the lung syndrome were selected from Dazhou Hospital of Integrated Traditional Chinese and Western Medicine.Based on their medication intention,the patients were divided into two groups,the experimental group and the control group,with 30 cases in each group.The control group received conventional Western medicine therapy,while the experimental group received additional treatment with Fuzi Shanyu Tang on this basis.Changes in inflammatory indicators and arterial blood gases were observed before and after treatment in both groups.Furthermore,changes in traditional Chinese medicine(TCM)symptom scores were observed in both groups to evaluate the clinical efficacy.Results:Following the administration of treatment,significant decreases in WBC,NEUT%,and hs-CRP were observed in the experimental group compared to the control group(P<0.05).Additionally,notable increases in PaO2 and SaO2 were evident in the experimental group following treatment,with levels higher than those in the control group.Conversely,a significant reduction in PaCO2 was noted in the experimental group with levels lower than the control group(P<0.05).Furthermore,TCM syndrome scores in the experimental group showed a substantial decrease,indicating a greater efficacy compared to the control group(P<0.05).The experimental group also demonstrated a higher rate of effectiveness compared with the control group(P<0.05).Conclusion:The modified Fuzi Shanyu Tang,exerts a significant anti-inflammatory effect in the treatment of phlegm-turbidity obstructing the lung syndrome in AECOPD.The decoction has been demonstrated to effectively inhibit airway inflammation,alleviate clinical symptoms,improve arterial blood gas indicators,and enhance quality of life of patients.关键词
慢性阻塞性肺疾病/痰浊阻肺证/附子山萸汤/动脉血气/炎症因子Key words
Chronic obstructive pulmonary disease/Phlegm-turbidity obstructing the lung syndrome/Fuzi Shanyu Tang/Arterial blood gas/Inflammatory factor分类
医药卫生引用本文复制引用
蒋明君,冉唯君,熊浪..附子山萸汤治疗慢性阻塞性肺疾病急性加重期痰浊阻肺证临床疗效观察[J].中医临床研究,2026,18(8):49-54,6.基金项目
国家高质量发展示范项目—老年健康服务体系项目(01202425). （01202425）
