中医杂志2026，Vol.67Issue(7)：803-807,5.DOI:10.13288/j.11-2166/r.2026.07.017
《伤寒杂病论》中枳实功效再探讨
Re-Examination of the Efficacy of Zhishi(Fructus Aurantii Immaturus)in Treatise on Cold Damage and Miscellaneous Diseases(《伤寒杂病论》)
摘要
Abstract
This study addresses the issue of understanding the efficacy of Zhishi(Fructus Aurantii Immaturus)in the Treatise on Cold Damage and Miscellaneous Diseases(《伤寒杂病论》)caused by changes in the botanical origin of the herbal medicinals.Through a historical tracing and theoretical exploration,the efficacy theory of Zhishi in the Han Dynasty is further discussed.Historical tracing shows that the botanical origin of Zhishi evolved from the mature fruit peel of Juju(Fructus Ponciri Trifoliatae)in the Han and Tang dynasties to the immature fruit of sour orange after the Song Dynasty.This evolution strengthened its function of"breaking stagnant qi and dispersing accumulation"but caused a disconnection between later theoretical interpretations of Zhishi and its Han Dynasty application.Analysis of formulas containing Zhishi and the herbal combinations in the Treatise on Cold Damage and Miscellaneous Diseases reveals that the functions have high similarity with records in the Miscellaneous Records of Famous Physicians(《名医别录》),and the effect trends are highly dependent on herbal combinations.The therapeutic range broadly covers the chest and abdomen rather than focusing solely on the lower jiao(焦).Therefore,accurately understanding the efficacy of Zhishi in the Treatise on Cold Damage and Miscellaneous Diseases requires returning to its Han Dynasty origin(mature fruit peel of Juju),where its properties lean more toward unblocking constraint via diffusing and dissipating rather than aggressively breaking constraint qi.关键词
枳实/本草考证/《伤寒杂病论》/药物功效Key words
Zhishi(Fructus Aurantii Immaturus)/materia medica verification/Treatise on Cold Damage and Miscel-laneous Diseases《伤寒杂病论》)/herbal efficacy引用本文复制引用
甄晨,梁锐霆,刘树林..《伤寒杂病论》中枳实功效再探讨[J].中医杂志,2026,67(7):803-807,5.基金项目
广州市科学技术局2025年度市校(院)企联合资助项目(2025A03J3995) （院）
广东省中医药局指令(委托)性项目(20243003) （委托）
