中医杂志2026，Vol.67Issue(8)：845-849,5.DOI:10.13288/j.11-2166/r.2026.08.007
肠易激综合征的中医时间医学时序治疗策略
Chronotherapy Strategy for Irritable Bowel Syndrome in Traditional Chinese Medicine Chronomedicine
摘要
Abstract
From the perspective of traditional Chinese medicine(TCM)chronomedicine,this article systemati-cally explored the inherent connection of rhythmic theories such as the waxing and waning of yin and yang,the ebb and flow of midnight and midday,and the movement of ying and wei levels,with the occurrence and development of irritable bowel syndrome(IBS).The core pathogenesis of IBS involves the liver failing to govern the free flow of qi,and the dysfunction of the spleen and stomach in ascending and descending.Circadian rhythm disruption can further exacerbate dysfunction of zang-fu(脏腑)organs by damaging the balance of yin-yang and ying-wei.The immune rhythm,microbiome rhythm,and neuroendocrine rhythm regulated by biological clock genes are highly consistent with the TCM theory of"correspondence between heaven and humankind".Therefore,it is proposed to adjust IBS treatment plans in accordance with natural rhythms,including temporal health preservation and management,temporal external therapies and temporal medication,in order to provide a new approach for the clinical diagnosis and treat-ment of IBS.关键词
肠易激综合征/中医时间医学/昼夜节律/脑-肠轴/肠道菌群Key words
irritable bowel syndrome/traditional Chinese medicine chronomedicine/circadian rhythm/brain-gut axis/gut microbiota引用本文复制引用
沈梦文,郭昕悦,王玮佳,马占龙,刘婷婷,魏雨欣,孙志广..肠易激综合征的中医时间医学时序治疗策略[J].中医杂志,2026,67(8):845-849,5.基金项目
国家自然科学基金(82274399,82574902) （82274399,82574902）
江苏省中医药科技发展委托专项(2022WTZX01) （2022WTZX01）
