Fundamental Research2026,Vol.6Issue(2):P.691-704,14.DOI:10.1016/j.fmre.2024.02.009
Incoherent feedforward loop dominates the robustness and tunability of necroptosis biphasic,emergent,and coexistent dynamics
Fei Xu 1Xiang Li 2Rui Wu 3Hong Qi 4Jun Jin 5Zhilong Liu 5Yuning Wu 6Hai Lin 7Chuansheng Shen 8Jianwei Shuai9
作者信息
- 1. Department of Physics and Fujian Provincial Key Laboratory for Soft Functional Materials Research,Xiamen University,Xiamen 361005,China Department of Physics,Anhui Normal University,Wuhu 241002,China
- 2. Department of Physics and Fujian Provincial Key Laboratory for Soft Functional Materials Research,Xiamen University,Xiamen 361005,China National Institute for Data Science in Health and Medicine and State Key Laboratory of Cellular Stress Biology,Innovation Center for Cell Signaling Network,School of Life Sciences,Xiamen University,Xiamen 361102,China
- 3. National Institute for Data Science in Health and Medicine and State Key Laboratory of Cellular Stress Biology,Innovation Center for Cell Signaling Network,School of Life Sciences,Xiamen University,Xiamen 361102,China
- 4. Complex Systems Research Center,Shanxi University,Taiyuan 030006,China
- 5. Department of Physics and Fujian Provincial Key Laboratory for Soft Functional Materials Research,Xiamen University,Xiamen 361005,China
- 6. Department of Mathematics and Physics,Fujian Jiangxia University,Fuzhou 350108,China
- 7. Oujiang Laboratory(Zhejiang Lab for Regenerative Medicine,Vision and Brain Health)and Wenzhou Institute,University of Chinese Academy of Sciences,Wenzhou 325001,China
- 8. School of Mathematics and Physics,Anqing Normal University,Anqing 246011,China
- 9. Department of Physics and Fujian Provincial Key Laboratory for Soft Functional Materials Research,Xiamen University,Xiamen 361005,China National Institute for Data Science in Health and Medicine and State Key Laboratory of Cellular Stress Biology,Innovation Center for Cell Signaling Network,School of Life Sciences,Xiamen University,Xiamen 361102,China Oujiang Laboratory(Zhejiang Lab for Regenerative Medicine,Vision and Brain Health)and Wenzhou Institute,University of Chinese Academy of Sciences,Wenzhou 325001,China
- 折叠
摘要
关键词
Incoherent feedforward loop/Biphasic dynamics/Emergence/Necroptosis/Design principle分类
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Fei Xu,Xiang Li,Rui Wu,Hong Qi,Jun Jin,Zhilong Liu,Yuning Wu,Hai Lin,Chuansheng Shen,Jianwei Shuai..Incoherent feedforward loop dominates the robustness and tunability of necroptosis biphasic,emergent,and coexistent dynamics[J].Fundamental Research,2026,6(2):P.691-704,14.基金项目
supported by the National Natural Science Foundation of China(12090052) (12090052)
the Ministry of Science and Technology of the People’s Republic of China(STI2030-Major Projects 2021ZD0201900) (STI2030-Major Projects 2021ZD0201900)
the Natural Science Foundation of Fujian Province of China(2023J05002) (2023J05002)
the Fundamental Research funds for the Central Universities(20720230017). (20720230017)