首页|期刊导航|Neural Regeneration Research|Integrated machine learning-based RNA sequencing and single-cell analysis reveal RNA methylation regulation patterns in the immune microenvironment of Alzheimer’s disease

Integrated machine learning-based RNA sequencing and single-cell analysis reveal RNA methylation regulation patterns in the immune microenvironment of Alzheimer’s disease

Shuguang Wu Ting Guo Xingyongpei Zheng Caihong Gu Yujie Hu Xinru Gu Xinyu Zhou

Neural Regeneration Research2026，Vol.21Issue(8)：P.3754-3768,15.

Neural Regeneration Research2026，Vol.21Issue(8)：P.3754-3768,15.DOI:10.4103/NRR.NRR-D-24-01650

Integrated machine learning-based RNA sequencing and single-cell analysis reveal RNA methylation regulation patterns in the immune microenvironment of Alzheimer’s disease

Shuguang Wu ¹Ting Guo ²Xingyongpei Zheng ³Caihong Gu ⁴Yujie Hu ⁵Xinru Gu ³Xinyu Zhou⁶

作者信息

1. Department of Anesthesiology,The Second Affiliated Hospital,Zhejiang University School of Medicine,Hangzhou,Zhejiang Province,China
2. Department of Geriatric Medicine,Shanghai Sixth People’s Hospital Affiliated to Shanghai Jiao Tong University School of Medicine,Shanghai,China
3. Department of Neurology,The Affiliated Lianyungang Hospital of Xuzhou Medical University,Lianyungang,Jiangsu Province,China
4. Department of Neurology,The First Affiliated Hospital of Kangda College of Nanjing Medical University,Lianyungang,Jiangsu Province,China
5. Department of Neurology,Nanjing Drum Tower Hospital,Affiliated Hospital of Medical School,Nanjing University,Nanjing,Jiangsu Province,China
6. Department of Neurology,The Affiliated Lianyungang Hospital of Xuzhou Medical University,Lianyungang,Jiangsu Province,China Department of Neurology,The First Affiliated Hospital of Kangda College of Nanjing Medical University,Lianyungang,Jiangsu Province,China Department of Neurology,Lianyungang Clinical College of Nanjing Medical University,Lianyungang,Jiangsu Province,China
折叠

摘要

关键词

Alzheimer’s disease/immunity/long non-coding RNAs/machine learning/nerve regeneration/risk model/RNA methylation

分类

医药卫生

引用本文复制引用

Shuguang Wu,Ting Guo,Xingyongpei Zheng,Caihong Gu,Yujie Hu,Xinru Gu,Xinyu Zhou..Integrated machine learning-based RNA sequencing and single-cell analysis reveal RNA methylation regulation patterns in the immune microenvironment of Alzheimer’s disease[J].Neural Regeneration Research,2026,21(8):P.3754-3768,15.

基金项目

supported by the Elderly Health Research Project of Jiangsu Province,No.LKM2023043(to XZ). （to XZ）

Neural Regeneration Research

ISSN：1673-5374

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