中医药临床杂志2026，Vol.38Issue(4)：647-652,6.DOI:10.16448/j.cjtcm.2026.0406
基于"形神一体"理论从肝肾脑探讨肝豆状核变性抑郁诊疗思路
Exploring Diagnostic and Treatment Strategies for Wilson's Disease Depression Based on the Theory of"Unity of Form and Spirit"from the Perspective of Liver,Kidney,and Brain
摘要
Abstract
Wilson's disease(WD)is a prevalent hereditary disease in my country.Depression associated with WD often presents atypically,sometimes preceding neurological symptoms,and is easily confused with the psychiatric symptoms of WD itself,severely impacting patients'daily lives and work.One of the fundamental principles of Tradi-tional Chinese Medicine(TCM)diagnosis is a holistic view.This article,centered on the concept of"the unity of form and spirit,"and combining previous research,elucidates the causes of depression in WD through the lens of the liver,kidneys,and brain.It proposes that liver Qi stagnation,kidney essence deficiency,and damage to both liver and kid-neys lead to pathogenic factors disturbing the brain's pathways,causing emotional abnormalities.Based on the prin-ciple of tonifying deficiency and purging excess,a treatment method of tonifying deficiency and eliminating pathogenic factors is proposed and applied clinically,providing a new diagnostic and treatment approach for depression in WD us-ing TCM.关键词
形神一体观/肝豆状核变性/抑郁/中药/针灸Key words
The unity of form and spirit/Wilson's disease/Depression/Traditional Chinese medicine/Acupuncture分类
医药卫生引用本文复制引用
朱欣雨,陈永华,杨文明..基于"形神一体"理论从肝肾脑探讨肝豆状核变性抑郁诊疗思路[J].中医药临床杂志,2026,38(4):647-652,6.基金项目
国家自然科学基金委员会,联合基金项目(U22A20366) （U22A20366）
安徽省高等学校科学研究项目自然科学类(2024AH051032) （2024AH051032）
安徽省中医药传承创新科研项目(2024CCCX001) （2024CCCX001）
