动物医学进展2026，Vol.47Issue(5)：117-122,6.
Ⅲ型CRISPR-Cas系统的技术概述
Technical Status of the Type Ⅲ CRISPR-Cas System
摘要
Abstract
The CRISPR-Cas(Clustered regularly interspaced short palindromic repeats-CRISPR associated proteins)system has brought revolutionary advances to many areas of biotechnology.Of all the types of CRISPR-Cas systems,type Ⅲ CRISPR-Cas system are the most complex,therefore may have special uses that cannot be achieved by other types of CRISPR-Cas systems.In this paper,we introduce the characteristics of type Ⅲ CRISPR-Cas system,as well as their special applications in improving genome manipulation,RNA interference,pathogen nucleic acid detection,transcription recording techniques,etc,and discuss the bottlenecks and possible solutions of current type Ⅲ CRISPR-Cas system applications.It provides a theoretical framework and innovative entry point for microbiology,gene editing,immunology and even biotechnology industry.关键词
Ⅲ型CRISPR-Cas系统/基因组编辑/RNA干扰/病原核酸检测/转录监测Key words
Type Ⅲ CRISPR-Cas system/Genome editing/RNA interference/Pathogen nucleic acid detection/Transcription monitoring分类
生物科学引用本文复制引用
孙克雄,李洁,刘慧丽,孙钰铠,王炳鑫,姜越秋,王静博,张信夫..Ⅲ型CRISPR-Cas系统的技术概述[J].动物医学进展,2026,47(5):117-122,6.基金项目
中国博士后科学基金第73批面上项目(2023M730996) （2023M730996）
河南农业大学拔尖人才项目(111/30501276) （111/30501276）
