动物医学进展2026，Vol.47Issue(5)：123-127,5.
表观遗传修饰在抗病育种中的应用潜力
The Application Potential of Epigenetic Modifications in Disease-resistant Breeding
摘要
Abstract
Disease-resistant breeding is one of the important strategies for animal disease prevention and control.At present,China has made great progress in this area through gene editing technology.But,there are uncertainties in its application transformation,because it may cause human genome confusion.Epigenetic modification is a new method of regulation through DNA,histone or chromosome modification,which has heritability and reversibility,and is a feasible method to solve the biosafety of disease resistance breeding.At present,African swine fever(ASF),porcine reproductive and respiratory syndrome(PRRS)and porcine epidemic diarrhea(PED)disease-related epigenetic modifications were used as breakthrough points to prove the feasibility of pig disease resistance breeding through epigenetic modifications,and provide reference for the transformation applica-tion of disease resistance breeding.关键词
表观遗传修饰/抗病育种/非洲猪瘟/猪繁殖于呼吸障碍综合征/猪流行性腹泻Key words
Epigenetic modifications/Disease-resistant breeding/African swine fever/Porcine reproductive and respiratory syndrome/Porcine epidemic diarrhea分类
农业科技引用本文复制引用
白国锋,邓彦飞..表观遗传修饰在抗病育种中的应用潜力[J].动物医学进展,2026,47(5):123-127,5.基金项目
国家重点研发计划项目(2023YFD1300502),广西壮族自治区自然科学基金项目(2023GXNSFAA026367) （2023YFD1300502）
