分子影像学杂志2026，Vol.49Issue(4)：522-528,7.DOI:10.12122/j.issn.1674-4500.2026.04.15
功能性近红外光谱技术在失眠障碍中的应用进展
Advances in the application of functional near-infrared spectroscopy in insomnia disorders
摘要
Abstract
The prevalence rate of insomnia is as high as 15％,presents limitations in traditional diagnostic methods for both mechanistic research and clinical assessment.Functional near-infrared spectroscopy(fNIRS)is an emerging non-invasive neural monitoring technique.fNIRS possesses the capability for direct monitoring of cerebral cortical haemodynamics,featuring a sampling rate of approximately 10Hz or higher and excellent resistance to motion artefacts.fNIRS has become an important tool for investigating the neural mechanisms of insomnia and for clinical monitoring.fNIRS can effectively monitor dynamic changes in oxyhaemoglobin levels within superficial cortical regions such as the prefrontal cortex in insomnia patients,as well as alterations in the connectivity state of the default mode network between certain cortical regions.fNIRS provides novel data supporting the exploration of neural circuit mechanisms underlying sleep-wake regulation.The combined application of fNIRS and multimodal technologies demonstrates potential for guiding personalised treatment.This paper systematically reviews the technical advantages and research progress of fNIRS in assessing brain function and monitoring treatment efficacy for insomnia disorders,aiming to advance the application of fNIRS in clinical research and facilitate the development of more precise objective assessment and intervention strategies for insomnia.关键词
功能性近红外光谱技术/失眠/前额叶皮质/脑网络/多模态Key words
functional near-infrared spectroscopy/insomnia/prefrontal cortex/brain networks/multimodal引用本文复制引用
陈卓,白林,张成宇,骆思宏,孙洪艺,孟子杭,李晓宁..功能性近红外光谱技术在失眠障碍中的应用进展[J].分子影像学杂志,2026,49(4):522-528,7.基金项目
国家中医药管理局高水平中医药重点学科建设项目(14061230010) （14061230010）
