高校化学工程学报2026，Vol.40Issue(2)：254-261,8.DOI:10.3969/j.issn.1003-9015.2025.00.050
基于LabVIEW的连续流动快速固相多肽合成
Continuous flow rapid solid-phase peptide synthesis based on LabVIEW
摘要
Abstract
In order to achieve automation and high efficiency in peptide solid-phase synthesis,a continuous-flow rapid solid-phase peptide synthesis system was developed.This system was developed by combining the programming capability of LabVIEW and the flow synthesis technology.In addition,the optimization strategy of single factor in continuous-flow mode was explored.The results demonstrated that,in comparison with the conventional solid-phase synthesis approach,the system shortened the reaction time by nearly 80%and decreased the reagents consumption by 60%,thereby exhibiting high synthetic efficiency and economic advantages.The crude peptide purity was found to be 90.20%for Argireline.The findings of this study demonstrated the capacity of the system to synthesize high-purity peptides in a brief period,thereby providing dependable technical support for the development and commercialization of peptide drugs.关键词
多肽/连续流动/LabVIEW/固相合成/自动合成Key words
peptides/continuous-flow/LabVIEW/solid-phase synthesis/automated synthesis分类
化学化工引用本文复制引用
苏酌,田浩澜,苏贤斌..基于LabVIEW的连续流动快速固相多肽合成[J].高校化学工程学报,2026,40(2):254-261,8.基金项目
江苏高校优势学科建设工程资助项目(PAPD). （PAPD）
