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New activities of homoyessotoxin against lung cancer through the regulation of EGFR/PI3K/AKT pathway

Kuilin Chen Xinyu Gao Jiapeng Li Shuhui Jia Xin Jiang Jin Zhou Weidong Xie

海洋生命科学与技术(英文)2026,Vol.18Issue(1):144-163,20.
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海洋生命科学与技术(英文)2026,Vol.18Issue(1):144-163,20.DOI:10.1007/s42995-026-00354-9

New activities of homoyessotoxin against lung cancer through the regulation of EGFR/PI3K/AKT pathway

New activities of homoyessotoxin against lung cancer through the regulation of EGFR/PI3K/AKT pathway

Kuilin Chen 1Xinyu Gao 1Jiapeng Li 1Shuhui Jia 2Xin Jiang 3Jin Zhou 4Weidong Xie5

作者信息

  • 1. State Key Laboratory of Chemical Oncogenomics,Shenzhen International Graduate School,Tsinghua University,Shenzhen 518055,China||Shenzhen Key Laboratory of Health Science and Technology,Institute of Biopharmaceutical and Health Engineering,Shenzhen International Graduate School,Tsinghua University,Shenzhen 518055,China
  • 2. State Key Laboratory of Chemical Oncogenomics,Shenzhen International Graduate School,Tsinghua University,Shenzhen 518055,China||Open FIESTA Center,Shenzhen International Graduate School,Tsinghua University,Shenzhen 518055,China
  • 3. Division of Hematology-Oncology,Boston Children's Hospital,Harvard Medical School,Boston,MA,USA
  • 4. Institute for Ocean Engineering,Shenzhen International Graduate School,Tsinghua University,Shenzhen 518055,China
  • 5. State Key Laboratory of Chemical Oncogenomics,Shenzhen International Graduate School,Tsinghua University,Shenzhen 518055,China||Shenzhen Key Laboratory of Health Science and Technology,Institute of Biopharmaceutical and Health Engineering,Shenzhen International Graduate School,Tsinghua University,Shenzhen 518055,China||Open FIESTA Center,Shenzhen International Graduate School,Tsinghua University,Shenzhen 518055,China
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摘要

关键词

Homoyessotoxin/Non-small cell lung cancer/EGFR/Apoptosis/Network pharmacology/Proteomics

Key words

Homoyessotoxin/Non-small cell lung cancer/EGFR/Apoptosis/Network pharmacology/Proteomics

引用本文复制引用

Kuilin Chen,Xinyu Gao,Jiapeng Li,Shuhui Jia,Xin Jiang,Jin Zhou,Weidong Xie..New activities of homoyessotoxin against lung cancer through the regulation of EGFR/PI3K/AKT pathway[J].海洋生命科学与技术(英文),2026,18(1):144-163,20.

基金项目

This research was supported by the Shenzhen Science and Technology Program(KCXFZ20230731093402005),the National Key R&D Program of China(2023YFA0914300(2023YFA0914302)),the program of the Shenzhen Key Laboratory of Advanced Technology for Marine Ecology(ZDSYS20230626091459009). (KCXFZ20230731093402005)

海洋生命科学与技术(英文)

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