机器人外科学杂志(中英文)2026,Vol.7Issue(4):594-599,6.DOI:10.12180/j.issn.2096-7721.2026.04.007
机器人辅助肝癌根治术治疗乙肝相关性肝癌的疗效分析
Efficacy of robot-assisted radical hepatectomy in the treatment of hepatitis B virus-related hepatocellular carcinoma
摘要
Abstract
Objective:To analyze the clinical efficacy of robot-assisted radical hepatectomy in the treatment of hepatitis B virus(HBV)-related hepatocellular carcinoma(HCC).Methods:120 patients with HBV-related HCC who underwent radical hepatectomy at Shengjing Hospital of China Medical University from January 2024 to June 2025 were enrolled.They were randomly divided into the control group(n=60,undergoing open radical hepatectomy)and the observation group(n=60,undergoing robot-assisted radical hepatectomy)using a random number table.Surgical indicators,postoperative recovery indicators,pain levels,and perioperative changes in liver function and inflammatory mediators were compared between the two groups.Results:The total operative time was longer in the observation group than that in the control group,while the total portal clamping time,resection margin distance,time to first ambulation,time to first flatus,time to first defecation,and total length of hospital stay were significantly shorter in the observation group(P<0.05).Intraoperative blood loss was significantly lower in the observation group than that in the control group(P<0.05).Visual analog scale(VAS)scores at 12 h,24 h,48 h,and 72 h postoperatively were all significantly lower in the observation group than those in the control group(P<0.05).3 days after surgery,the magnitudes of change in ALT,AST,TBil,IL-6,CRP,ALB,and TNF-α were significantly smaller in the observation group than those in the control group(P<0.05).Conclusion:Compared with open radical hepatectomy,robot-assisted radical hepatectomy has greater advantages in treating HBV-related HCC.It can enhance overall surgical efficiency,reduce surgical trauma,ensure complete tumor resection,thereby promoting postoperative recovery,reducing liver function impairment and decreasing systemic inflammatory response.关键词
机器人辅助手术/开腹手术/肝癌根治术/乙肝相关性肝癌/肝功能/炎症介质Key words
Robot-assisted Surgery/Open Surgery/Radical Hepatectomy/Hepatitis B Virus-related Hepatocellular Carcinoma/Liver Function/Inflammatory Mediators分类
医药卫生引用本文复制引用
刘琳,刘宏威,周建,杨佳,张凌..机器人辅助肝癌根治术治疗乙肝相关性肝癌的疗效分析[J].机器人外科学杂志(中英文),2026,7(4):594-599,6.基金项目
辽宁省自然科学基金指导计划项目(2022-JM-0367) Liaoning Provincial Natural Science Foundation Guiding Program(2022-JM-0367) (2022-JM-0367)