药学研究2026，Vol.45Issue(4)：424-433,10.DOI:10.13506/j.cnki.jpr.2026.04.010
三维荧光技术在药物研究中的应用
Translation of three-dimensional fluorescence technology in pharmaceutical research
摘要
Abstract
Three-dimensional fluorescence spectroscopy,a novel spectral analysis technique that has rapidly developed in recent years,demonstrates unique application value in modern pharmaceutical research due to its capability of multidi-mensional spectral information acquisition and high-sensitive detection.By constructing excitation-emission matrix spectra,this technology enables synchronous acquisition of fluorescence emission characteristics under multiple excitation wave-lengths,thus achieving component analysis of complex drug systems.With its advantages of accuracy,rapidity,and non-de-structiveness,three-dimensional fluorescence spectroscopy shows promising application potential in fields such as drug iden-tification,quantitative analysis,detection of exogenous harmful substances,and pharmacological mechanism research.This paper reviewed the latest application advances of three-dimensional fluorescence technology in pharmaceutical research,deeply analyzed its advantageous characteristics,and forecastd its future development potential,aiming to provide theoretical references and technical guidance for the innovative application of this technology in the pharmaceutical field.关键词
三维荧光技术/药物鉴别/定量分析/外源性有害物质检测/药理学研究Key words
Three-dimensional fluorescence spectroscopy/Drug identification/Quantitative analysis/Detection of exog-enous harmful substances/Pharmacological research分类
医药卫生引用本文复制引用
谢凌云,焦阳,汪冰,于雅萌,徐兴燕,牛艳,尹雪,薛菲,李世文,林永强..三维荧光技术在药物研究中的应用[J].药学研究,2026,45(4):424-433,10.基金项目
国家重点研发计划-中医药现代化专项(No.2023YFC3504102) （No.2023YFC3504102）
泉城产业领军人才支持计划创新团队项目(No.MRJT2105) （No.MRJT2105）
"新高校 20 条"科研带头人工作室项目(No.202228096) （No.202228096）
