基础医学教育2026，Vol.28Issue(4)：313-318,6.DOI:10.13754/j.issn2095-1450.2026.04.03
转录组分析融入医学遗传学课程的教学设计
Teaching design for the integration of transcriptome analysis into the course of medical genetics
摘要
Abstract
There are challenges of complex technical workflows and insufficient integration with clinical diagnostics in the teaching of transcriptomic technologies for the course of medical genetics.To address these issues,the authors develop a teaching framework,which is oriented to precision medicine and centered on transcriptomics.This framework encompasses three interconnected dimensions:fundamental techniques,clinical application,and teaching integration.It comprehensively covers the standard analytical procedures,from data quality control and expression quantification to differential analysis and functional annotation,and it also incorporates real-world diagnostic cases of genetic disorders and public genomic datasets available into teaching practice.With modular design,visualiza-tion tools,and stepwise project-based learning,the framework aims to deepen students'understanding of transcriptomic principles and enhance their ability to apply these techniques to both mechanism research and clinical diagnosis of genetic diseases.The proposed model provides a practical framework to integrate the leading edge and practicality of medical genetics teaching.关键词
医学遗传学/转录组学/实践教学/教学改革/基础临床融合Key words
medical genetics/transcriptomics/practical teaching/teaching reform/integration of basic techniques and clini-cal application分类
医药卫生引用本文复制引用
刘焕举,宿可,陈美婷,何崔同,戴智慧,肖邦,尹昊瓒,杨富..转录组分析融入医学遗传学课程的教学设计[J].基础医学教育,2026,28(4):313-318,6.基金项目
海军军医大学精品课程教材立项培育基金资助项目 （）
海军军医大学基础医学院"宜张"人才培育计划基金资助项目(JCYZRC-D-023) （JCYZRC-D-023）
