生物加工过程2026，Vol.24Issue(2)：209-218,10.DOI:10.3969/j.issn.1672-3678.2026.02.011
纳米普鲁士蓝及其金属掺杂在抗肿瘤领域的研究进展
Recent advances in anti-tumor application of Prussian blue nanoparticles and their metal doping
摘要
Abstract
Prussian blue(PB)has been approved by the Food and Drug Administration(FDA)as a clinical drug with good biosafety.PB nanoparticles have garnered significant attention in the field of biomedicine due to their strong near-infrared absorption,paramagnetism,various enzyme-like activities,stable chemical properties,tunable pore size,and ease of functionalization.This paper reviews the applications of PB nanoparticles in anti-tumor research,including photothermal therapy,drug delivery,regulation of reactive oxygen species,and in vivo imaging.Additionally,the review highlights the critical roles of metal-doped PB nanoparticles and their recent advancements in enhancing photothermal efficiency,catalytic activity within the tumor microenvironment,and the efficiency of multimodal diagnosis and therapy.关键词
普鲁士蓝/抗肿瘤/纳米材料/金属掺杂/类酶Key words
Prussian blue/anti-tumor/nanomaterials/metal doping/enzyme-like分类
医药卫生引用本文复制引用
班倩,侯禹洋,钟梦玲,周艳芬,李鑫,张琪..纳米普鲁士蓝及其金属掺杂在抗肿瘤领域的研究进展[J].生物加工过程,2026,24(2):209-218,10.基金项目
江苏省教育厅省高校(自然科学)面上项目(20KJB150021) （自然科学）
南京市生命健康科技专项——临床前沿技术突破(202110015) （202110015）
