中国当代儿科杂志2026，Vol.28Issue(5)：556-562,7.DOI:10.7499/j.issn.1008-8830.2510016
新生儿坏死性小肠结肠炎术中低体温对近期预后的影响
Effect of intraoperative hypothermia on short-term prognosis in neonatal necrotizing enterocolitis
摘要
Abstract
Objective To investigate the effect of intraoperative hypothermia on short-term prognosis in neonates with necrotizing enterocolitis(NEC)undergoing surgery.Methods Clinical data of 150 neonates with NEC who underwent surgery at Children's Hospital of Chongqing Medical University from June 2017 to August 2023 were retrospectively collected.Based on the lowest intraoperative temperature,patients were classified into a normothermia group(≥36.0℃,n=49),a mild hypothermia group(35.0-35.9℃,n=73),a moderate hypothermia group(34.0-34.9℃,n=20),and a severe hypothermia group(<34.0℃,n=8).Postoperative outcomes were analyzed across groups.Results Intraoperative hypothermia occurred in 101/150(67.3%)neonates.Mild hypothermia significantly increased the risk of postoperative coagulation disorders(OR=2.170,95%CI:1.035-4.552,P<0.05).Postoperative hospital stay was significantly prolonged in the mild(B=12.250,95%CI:1.176-23.324,P<0.05)and severe hypothermia groups(B=24.510,95%CI:1.645-47.376,P<0.05),while the duration of central venous catheterization was significantly increased in the moderate hypothermia group(B=11.388,95%CI:1.625-21.15,P<0.05).Conclusions Intraoperative hypothermia is common in neonates with NEC undergoing surgery,and different degrees of hypothermia are associated with distinct adverse effects on short-term prognosis.Intraoperative temperature management should be prioritized,and active warming measures should be implemented to improve outcomes.关键词
坏死性小肠结肠炎/术中低体温/近期预后/新生儿Key words
Necrotizing enterocolitis/Intraoperative hypothermia/Short-term prognosis/Neonate引用本文复制引用
冉芹,韦红,史源,王政力..新生儿坏死性小肠结肠炎术中低体温对近期预后的影响[J].中国当代儿科杂志,2026,28(5):556-562,7.基金项目
重庆市自然科学基金面上项目(CSTB2023NSCQ-MSX0178) （CSTB2023NSCQ-MSX0178）
江西省自然科学基金杰青项目(20242BAB23079). （20242BAB23079）
