中国中医急症2026，Vol.35Issue(4)：446-449,4.DOI:10.3969/j.issn.1004-745X.2026.04.016
三拗汤加味联合西药治疗小儿喘息性支气管炎临床观察
Clinical Observation of Modified San'ao Decoction Combined with Western Medicine in the Treatment of Children with Asthmatic Bronchitis
摘要
Abstract
Objective:To investigate the clinical efficacy of Modified San'ao Decoction combined with Western medicine in the treatment of children with asthmatic bronchitis.Methods:A total of 106 child patients were ran-domly divided into the two groups(53 cases in each group)by block randomization method.The control group re-ceived aerosol inhalation therapy,and the observation group received additional Modified San'ao Decoction on the basis of the control group.The improvement of clinical symptoms(disappearance time of pulmonary rales,disap-pearance time of wheezing,cough cessation time),levels of airway inflammatory markers(eosinophil cationic pro-tein,interleukin-6,C-reactive protein),pulmonary function indicators(time to peak ratio,volume to peak ratio,re-spiratory rate),TCM syndrome scores,immune indicators and clinical efficacy were observed and compared be-tween the two groups before and after treatment.Results:The symptom improvement in the observation group was faster than that in the control group(P＜0.05).After treatment,the serum eosinophil cationic protein,interleukin-6,C-reactive protein,respiratory rate,TCM syndrome scores and CD8+in both groups were decreased,while the time to peak ratio,volume to peak ratio,the CD4+levels and CD4+/CD8+ratio were increased compared with those before treatment,and the improvement in the observation group was significantly better than that in the control group(P＜0.05).Conclusion:Modified San'ao Decoction combined with Western medicine has significant clini-cal efficacy in the treatment of children with asthmatic bronchitis.关键词
喘息性支气管炎/儿童/三拗汤/气道炎症/肺功能/免疫功能Key words
Asthmatic bronchitis/Children/San'ao Decoction/Airway inflammation/Pulmonary function/Im-mune function分类
医药卫生引用本文复制引用
孙秀娟,马新江,高健,李云亮..三拗汤加味联合西药治疗小儿喘息性支气管炎临床观察[J].中国中医急症,2026,35(4):446-449,4.基金项目
2023年度山东省中医药科技项目(Z-2023025) （Z-2023025）
