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麦粒灸联合西医常规治疗乙肝肝硬化腹水临床研究

李君 周超 刘慧 徐笑 雒琳 秦培洁

中国中医药信息杂志2026,Vol.33Issue(5):131-136,6.
中国中医药信息杂志2026,Vol.33Issue(5):131-136,6.DOI:10.19879/j.cnki.1005-5304.202508579

麦粒灸联合西医常规治疗乙肝肝硬化腹水临床研究

Clinical Study on Grain-sized Moxibustion Combined with Conventional Western Medicine for the Treatment of Ascites Due to Cirrhosis of Hepatitis B

李君 1周超 2刘慧 1徐笑 1雒琳 3秦培洁1

作者信息

  • 1. 中国中医科学院中国医史文献研究所,北京 100700
  • 2. 解放军总医院第五医学中心,北京 100039
  • 3. 中国中医科学院中医临床基础医学研究所,北京 100700
  • 折叠

摘要

Abstract

Objective To observe the clinical efficacy and safety of grain-sized moxibustion combined with conventional Western medicine for the treatment of ascites due to cirrhosis of hepatitis B.Methods Totally 78 patients with ascites due to cirrhosis of hepatitis B were randomly divided into experimental group and control group,with 39 cases in each group.The control group received conventional Western medicine treatment,while the experimental group received additional treatment with grain-sized moxibustion for 10 days,with 3-month follow-up.The total effective rates of ascites treatment of both groups were observed,and abdominal circumference,body mass,24-hour urine output,main symptom score,liver function indicators between the two groups were compared.Adverse reactions in two groups were monitored.Results Compared with the control group,the total effective rate of the experimental group significantly increased on days 11,60 and 90(P<0.05).Two cases of refractory ascites achieved clinical remission by day 6,with significant reductions in abdominal circumference on day 6 and body mass on day 90(P<0.05).The total symptom score showed significant improvement on day 60(P<0.05),while the ALP level decreased significantly on day 11(P<0.05);compared with before treatment,the 24-hour urine output in the experimental group increased significantly by day 6(P<0.05),fatigue scores improved significantly on days 11,30 and 60(P<0.05),liver function indicators ALT and AST decreased significantly by day 6(P<0.05).There were no significant differences in blood,urine,stool routine,renal function,and electrocardiogram in the two groups before and after treatment.No adverse reactions were reported.Conclusion The addition of grain-sized moxibustion on the basis of conventional Western medicine treatment can improve the total effective rate of treatment of ascites due to hepatitis B cirrhosis,increase urine volume,reduce abdominal circumference and body mass,and have a lasting effect;it can improve liver function and major symptoms,especially for refractory ascites,with good safety.

关键词

乙肝/肝硬化腹水/臌胀/艾灸/麦粒灸

Key words

hepatitis B/cirrhotic ascites/tympanites/moxibustion/grain-sized moxibustion

分类

医药卫生

引用本文复制引用

李君,周超,刘慧,徐笑,雒琳,秦培洁..麦粒灸联合西医常规治疗乙肝肝硬化腹水临床研究[J].中国中医药信息杂志,2026,33(5):131-136,6.

基金项目

首都卫生发展科研专项(首发2022-2-4311) (首发2022-2-4311)

中国中医科学院基本科研业务费自主选题(ZZ150513、ZZ160505) (ZZ150513、ZZ160505)

中国中医药信息杂志

1005-5304

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