中国中医眼科杂志2026，Vol.36Issue(5)：434-439,454,7.DOI:10.13444/j.cnki.zgzyykzz.2026.05.006
基于数据挖掘探讨《审视瑶函》中医眼科外治法用药规律
Analysis of Medication Rules for External Therapies in Ophthalmology of Shen Shi Yao Han Based on Data Mining
摘要
Abstract
OBJECTIVE To analyze the medication rules of Chinese medicines involved in the external treatments recorded in Shen Shi Yao Han using data mining technology,and to provide diagnostic ideas and medication experience for clinical external treatment with Chinese medicines.METHODS Chinese medicines explicitly recorded for external treatments in Shen Shi Yao Han were collected and entered into Excel 2019 software to establish a database.After standardizing the Chinese medicine names,administration routes were statistically analyzed.The data were then imported into the Traditional Chinese Medicine Inheritance Computing Platform V3.5 to analyze medicine properties including four natures,five flavors,meridian tropism,efficacy,and usage frequency.The"Prescription Analysis"module was used for cluster analysis and association rule analysis.RESULTS(1)Medicine properties:A total of 84 prescriptions involving 206 Chinese medicines with a cumulative frequency of 607 uses were included.Regarding the four natures,cold-nature Chinese medicines were the most common(280 times,46.13％).Regarding the five flavors,pungent flavor Chinese medicines were the most common(269 times,32.18％).Regarding meridian tropism,Chinese medicines targeting Liver meridian were the most common(346 times,21.21％).(2)Administration routes:Eleven administration routes were involved.The top five were eye dropping(40 times,47.06％),eye washing(11 times,12.94％),nasal insufflation(seven times,8.24％),eye application(6 times,7.06％),and nose blowing,eye coating,eye rubbing(five times each,5.88％).(3)Usage frequency:Twenty-nine medicines were high-frequency Chinese medicines(used≥10 times).The top five were Coptidis rhizoma(27 times,32.14％),Angelicae sinensis radix(22 times,26.19％),Borneolum syntheticum(19 times,22.62％),Saposhnikoviae radix and cinnabaris(17 times each,20.24％).(4)Efficacy classification:Heat-clearing Chinese medicines were the most common(146 times,24.05％),followed by exterior-relieving Chinese medicines(98 times,16.14％),blood-activating and stasis-resolving Chinese medicines(57 times,9.39％),deficiency-tonifying Chinese medicines(49 times,8.07％),and toxin-removing,putrefaction-resolving,and flesh-engendering Chinese medicines(39 times,6.43％).(5)Cluster analysis:Four prescription clusters were identified.Cluster Ⅰ efficacy was dispelling wind and dispersing cold,moving Qi and activating blood.Cluster Ⅱ efficacy was clearing heat and disinhibiting dampness,removing putrefaction and engendering flesh.Cluster Ⅲ efficacy was clearing heat and resolving toxicity,dispersing swelling and stopping pain.Cluster Ⅳ efficacy was clearing heat and resolving toxicity,brightening the eyes and removing screen.(6)Association rule analysis:Fifteen Chinese medicine pairs were obtained.The top five associated pairs were Coptidis rhizoma and Schizonepetae herba-Saposhnikoviae radix;Myrrha-Olibanum;Asari herba-Saposhnikoviae radix;Paeoniae rubra radix-Angelicae sinensis radix;Margarita-Cinnabaris.CONCLUSIONS The external treatments in ophthalmology of Shen Shi Yao Han are guided by the principles of clearing heat,dispelling wind,resolving toxicity,and activating blood.The medicines are mostly cold and pungent,entering liver meridian.The primary dosage forms are eye dropping and eye washing,with adept use of mineral and animal Chinese medicines,reflecting the academic thought of expelling pathogenic factors and supporting healthy Qi,and treating different diseases with the same method.关键词
审视瑶函/药物外治/数据挖掘/用药规律/关联规则Key words
Shen Shi Yao Han/external treatment with Chinese medicines/data mining/medication rules/association rules分类
医药卫生引用本文复制引用
陈竹鹏,陈成,罗燕,郑博元,殷天凤,朱玉莲..基于数据挖掘探讨《审视瑶函》中医眼科外治法用药规律[J].中国中医眼科杂志,2026,36(5):434-439,454,7.基金项目
云南省科技厅基金项目(202301AZ070001-072) （202301AZ070001-072）
