中国中医骨伤科杂志2026，Vol.34Issue(5)：51-57,7.DOI:10.20085/j.cnki.issn1005-0205.260508
消肿镇痛散外敷联合超短波治疗急性踝关节扭伤——基于距腓后韧带修复与足背动脉血流改善的机制探讨
Effects of External Application of Xiaozhong Zhentong Powder Combined with Ultra Short Wave Therapy on the Thickness of the Posterior Talofibular Ligament and the Dorsal Foot Artery Blood Flow in Patients with Acute Ankle Sprain
摘要
Abstract
Objective:Based on the traditional Chinese medicine(TCM)pathogenesis of Qi stagnation and blood stasis syn-drome,to verify the synergistic effect of external application of Xiaozhong Zhentong powder(XZTS)and ultra short wave therapy in patients with acute ankle sprain(AAS),and to clarify its underlying mechanism in promoting posterior talofib-ular ligament(PTFL)repair and improving dorsal foot artery hemodynamics.Methods:A total of 118 patients with AAS within 72 h and diagnosed with the syndrome of Qi stagnation and blood stasis were randomly assigned(1∶1)to single therapy group(ultra short wave alone)or combined therapy group(XZTS external application+ultra short wave),with 59 cases in each group,for a 2-weeks treatment course.Visual analogue scale(VAS)score,ankle circumference,PTFL thickness,peak systolic velocity(PSV),mean flow velocity(MFV)and resistance index(RI)of the dorsal foot artery were measured before and after treatment,and effect sizes(Cohen's d)were calculated.Results:At baseline,there were no significant differences in VAS score,ankle circum-ference,PTFL thickness(both about 3.7 mm)and PSV(both about 2.9 cm/s)between the two groups(all P>0.05).After 2 weeks of treatment,VAS score in the combined therapy group decreased from(7.07±0.87)points to(1.32±0.34)points,and ankle circumference decreased from(41.25±2.77)cm to(36.29±1.22)cm,both significantly lower than those in the single therapy group(P<0.001).Compared with the single therapy group,PTFL thickness in the com-bined therapy group showed an additional reduction of 0.28 mm(Cohen's d=0.89,P<0.001),while PSV increased by an additional 0.39 cm/s(Cohen's d=0.92,P<0.001),accompanied by a greater increase in MFV and a more pro-nounced decrease in RI.Mechanistically,the combined therapy regimen exerts a synergistic effect of"anti-inflammatory and anti-edema,improvement of microcirculation,and promotion of ligament repair",thereby simultaneously correcting PTFL thickness abnormalities and dorsal foot artery blood flow disturbances.Conclusion:External application of XZTS combined with ultra short wave therapy can significantly relieve acute pain and swelling,improve PTFL structural repair and dorsal foot artery hemodynamics in patients with AAS,providing a safe and effective integrative TCM and Western medicine option for acute ankle sprain.No serious adverse events occurred during the study;mild skin burning was repor-ted in 2 cases(3.39%)in the combined therapy group,and transient dizziness in 1 case(1.69%)in the single therapy group,all of which resolved after symptomatic management.关键词
急性踝关节扭伤/消肿镇痛散/超短波/中西医结合/气滞血瘀证/距腓后韧带/足背动脉/血流动力学Key words
acute ankle sprain/Xiaozhong Zhentong powder/ultra short wave/integrative Chinese and Western medicine/syndrome of Qi stagnation and blood stasis/posterior talofibular ligament/dorsalis pedis artery/hemodynamics分类
医药卫生引用本文复制引用
张彦东,蔡同川,李显..消肿镇痛散外敷联合超短波治疗急性踝关节扭伤——基于距腓后韧带修复与足背动脉血流改善的机制探讨[J].中国中医骨伤科杂志,2026,34(5):51-57,7.基金项目
中国中医科学院西苑医院中医药临床科研一体化平台建设专项基金项目(XYZX0405-12) （XYZX0405-12）
