北京中医药大学学报2026，Vol.49Issue(5)：601-606,6.DOI:10.3969/j.issn.1006-2157.2026.05.002
基于气街理论探讨荆防败毒散治疗PM2.5致肺损伤的"枢转气机"效应
Exploring the"qi movement-pivoting"effect of Jingfang Baidu Powder in treating PM2.5-induced lung injury based on the qi pathway theory
摘要
Abstract
PM2.5-induced lung injury has emerged as a major public health concern.Western medicine currently lacks targeted curative approaches,whereas existing research in traditional Chinese medicine(TCM)has focused primarily on localized pathological mechanisms of the lung,with insufficient attention paid to the holistic perspective of meridian-qi-blood circulation.The classical theory of"lung failure in dispersion and descent"is limited to describing abnormalities in the rhythmic flow of qi,thus failing to encompass the complex pathological state of this disease.Consequently,drawing on the qi pathway theory and considering the composite pathogenic characteristics of PM2.5,which encompasses wind,cold,dampness,turbidity,and toxicity,this paper systematically elucidates the core pathogenesis of PM2.5-induced lung injury as"obstruction of the thoracic qi pathway by turbid toxins."This disruption leads to impaired pivoting movement of qi dynamics,subsequently inducing metabolic disorders of qi,blood,and body fluids,as well as lung-collateral damage.The disease progression evolves through three distinct stages:"qi pathway obstruction-pivoting dysfunction-systemic involvement."Jingfang Baidu Powder,through its precisely balanced composition of sovereign,minister,assistant,and envoy herbs,establishes a comprehensive therapeutic system aimed at"unblocking the pathway and restoring pivoting movement of qi."This offers a novel theoretical framework for the TCM-based diagnosis and treatment of PM2.5-related lung diseases,while also expanding the modern application of classical formulations.关键词
气街/胸气街/PM2.5/肺损伤/荆防败毒散Key words
qi pathway/thoracic qi pathway/PM2.5/lung injury/Jingfang Baidu Powder分类
医药卫生引用本文复制引用
邵威,程发峰,王雪茜,姚景春,徐燕,王庆国..基于气街理论探讨荆防败毒散治疗PM2.5致肺损伤的"枢转气机"效应[J].北京中医药大学学报,2026,49(5):601-606,6.基金项目
国家中医药管理局北京中医药薪火传承"3+3"工程项目(No.2025-SZ-C-97) （No.2025-SZ-C-97）
北京中医药大学横向课题(No.BUCM-2024-JS-FW-125) Beijing Traditional Chinese Medicine Inheritance Project"3+3"of the National Administration of Traditional Chinese Medicine(No.2025-SZ-C-97) （No.BUCM-2024-JS-FW-125）
