分析化学2026，Vol.54Issue(4)：554-567,中插1-中插6,20.DOI:10.19756/j.issn.0253-3820.251324
基于纳米材料的心肌肌钙蛋白Ⅰ分析方法研究进展
Recent Progress in Nanomaterials-based Analytical Methods for Detection of Cardiac Troponin Ⅰ
摘要
Abstract
Cardiac troponin I(cTnI)exhibits high specificity and sensitivity for myocardial injury,serving as a crucial biomarker for the early diagnosis of high-risk cardiovascular diseases(CVD),such as acute myocardial infarction(AMI).Recently,to meet the demand for early screening of high-risk CVD,various nanomaterial-based analytical methods with high-performance have been developed for the precise detection of low-abundance cTnI in blood samples.This review summarized recent research advancements over the past five years,focusing on the physicochemical properties of different nanomaterials to enhance the performance of electrochemical and optical detection methods for cTnI.It also discussed the limitations and prospects of as-developed methods in clinical applications,providing a detailed outline for the development of new methods for precise early screening of high-risk CVD.关键词
心肌肌钙蛋白I/生物传感器/心血管疾病/即时检验/评述Key words
Cardiac troponin I/Biosensors/Cardiovascular disease/Point-of-care testing/Review引用本文复制引用
李铸衡,王令萱,吴复超,宋丹,王皓冬,王振新..基于纳米材料的心肌肌钙蛋白Ⅰ分析方法研究进展[J].分析化学,2026,54(4):554-567,中插1-中插6,20.基金项目
吉林省自然科学基金-国家重点实验室(学科类)重大专项(No.SKL202302030)资助. Supported by the Natural Science Foundation of Jilin Province-Key Special Project of National Key Laboratory(No.SKL202302030). （学科类）
