广东农业科学2026，Vol.53Issue(3)：96-105,10.DOI:10.16768/j.issn.1004-874X.2026.03.009
利巴韦林水剂制备研究及其对草地贪夜蛾和斜纹夜蛾的防效
Development of Ribavirin Aqueous Solution and Its Control Efficacy to Spodoptera frugiperda and S.litura
摘要
Abstract
[Objective]Ribavirin is a broad-spectrum antiviral drug and exhibits good insecticidal activity against lepidopteran pests.To further determine its actual control efficacy,a ribavirin aqueous solution was prepared and evaluated against lepidopteran pests.[Method]Based on the high water solubility of ribavirin,the optimal wetting agent was selected from five commonly used ones(Morwet EFW,Morwet D-425,EL-30,EL-40,and Nongru 605)by indicator measurement,and a 5％ribavirin aqueous solution was prepared.Its control efficacy against Spodoptera frugiperda and S.litura was evaluated by stem and leaf spray application.[Result]The formulations obtained by mixing ribavirin with the five wetting agents appeared as light yellow homogeneous transparent,brown homogeneous transparent,milky white homogeneous,yellowish-white homogeneous,and colorless homogeneous transparent,respectively,with contact angles of 23.6°,57.5°,42.2°,35.8°,and 46.3°.All five formulations showed homogeneous dilution stability without precipitation,a foaming volume of 0.8 mL,and pH values ranging from 6.6 to 6.8.In thermal storage stability tests,the formulations prepared with Morwet EFW and Morwet D-425 remained homogeneous without precipitation;all formulations showed homogeneous without precipitation under cold storage conditions.These results indicate that the formulation prepared with Morwet EFW exhibited the best overall performance.Indoor efficacy tests showed that the 5％ribavirin aqueous solution diluted to 2 000 mg/L achieved the best control efficacy against S.frugiperda and S.litura on the 5th day after application,with control efficacies of 87.15％and 88.30％,respectively.The control efficacy was comparable to that of the control insecticide RH-5849(88.83％and 84.80％),and some treatment groups showed better control efficacy than the control.[Conclusion]The 5％ribavirin aqueous solution exhibits good control efficacy against S.frugiperda and S.litura.These results provide a theoretical basis for its application in actual agricultural production.关键词
利巴韦林/草地贪夜蛾/斜纹夜蛾/室内模拟/防效Key words
ribavirin/Spodoptera frugiperda/S.litura/laboratory simulation/control efficacy分类
农业科技引用本文复制引用
王柯,原泽,廖焕,苗菲,徐莉,余昊,刘润强,李冬植..利巴韦林水剂制备研究及其对草地贪夜蛾和斜纹夜蛾的防效[J].广东农业科学,2026,53(3):96-105,10.基金项目
河南省高等学校重点科研项目(24A210003) （24A210003）
中原科技创新青年拔尖人才项目 （）
河南省重点研发与推广专项(科技攻关)(252102110203) （科技攻关）
