赣南医科大学学报2026,Vol.46Issue(4):341-347,7.DOI:10.3969/j.issn.2097-7174.2026.04.008
经皮耳迷走神经电刺激在神经退行性疾病中的应用:聚焦阿尔茨海默病与帕金森病
Transcutaneous auricular vagus nerve stimulation in neurodegenerative diseases:focusing on Alzheimer's disease and Parkinson's disease
胡倩 1王嘉晟 1曹睿扬 1刘文楷 1王力峰 2王万辉2
作者信息
- 1. 赣南医科大学第一临床医学院
- 2. 赣南医科大学第一附属医院麻醉手术中心||赣州市麻醉学重点实验室,江西 赣州 341000
- 折叠
摘要
Abstract
Neurodegenerative diseases(NDDs)are a group of chronic,progressive neurological disorders characterized by the degeneration,death,and functional loss of neurons and glial cells,with Alzheimer's disease(AD)and Parkinson's disease(PD)being the most common types.At present,due to an incomplete understanding of their pathogenesis,existing therapeutic strategies remain limited in their ability to halt disease progression.Transcutaneous auricular vagus nerve stimulation(taVNS)is a safe and non-invasive neuromodulation technique that offers advantages over traditional therapeutic approaches,including fewer side effects and better tolerability.In recent years,taVNS has garnered increasing attention as an emerging therapeutic approach for the treatment of neurodegenerative diseases.This review focuses on AD and PD,discussing the potential mechanisms and therapeutic applications of taVNS in the prevention and treatment of these disorders,with the aim of providing novel insights for clinical management.关键词
经皮耳迷走神经电刺激/神经变性疾病/阿尔茨海默病/帕金森病/氧化应激/神经炎症Key words
Transcutaneous auricular vagus nerve stimulation/Neurodegenerative diseases/Alzheimer's disease/Parkinson's disease/Oxidative stress/Neuroinflammation分类
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胡倩,王嘉晟,曹睿扬,刘文楷,王力峰,王万辉..经皮耳迷走神经电刺激在神经退行性疾病中的应用:聚焦阿尔茨海默病与帕金森病[J].赣南医科大学学报,2026,46(4):341-347,7.