国际老年医学杂志2026，Vol.47Issue(3)：268-278,11.DOI:10.3969/j.issn.1674-7593.2026.03.003
季风气候地区空气污染物短期暴露与急性心力衰竭患者就诊的相关性分析
Analysis of correlation between short-term exposure of air pollutants and treatment of patients with acute heart failure in monsoon climate area
摘要
Abstract
Objective To explore the correlation analysis between short-term exposure of air pollutants and patients with a-cute heart failure in monsoon climate area.Methods The information of patients with acute heart failure in anzhen hospital from Janu-ary 2018 to December 2022,and the data of air pollutants and meteorology in the same period were continuously included,including carbon monoxide(CO),nitrogen dioxide(NO2),ozone(O3),sulfur dioxide(SO2),fine particles(PM2.5)and inhalable particles(PM10),daily average temperature and relative humidity.The generalized linear regression model was used to analyze the relationship between different air pollutants and patients with acute heart failure.Results In this study,CO、NO2 and SO2 were found to be posi-tively associated with the risk of acute heart failure(AHF)emergency visits.In the case of SO2,a significant association was observed between each 10 μg/m3 increase in concentration and a single-day lag effect(Lag 0),with a RR of 1.085(95%CI:1.026 to 1.147).The RR values of multi-day cumulative effect(Lag 01 to Lag 04)were 1.104,1.133,1.163 and 1.192,all of which were statistically significant and which exhibited an upward trend with the cumulative days increase.Statistically significant multi-day cumu-lative effects(Lag 01 to Lag 04)were also identified(P<0.05),and RR values were 1.104,1.133,1.163 and 1.192 in turn,indi-cating a rising trend with longer cumulative exposure days.In gender-stratified analyses,significant associations were found in males for both the single-day Lag(Lag 0)and multi-day cumulative effects(Lag 01 to Lag 04)of SO2,where the RR increased from 1.127 to 1.263,demonstrating a cumulative exposure-response pattern.In age-stratified analyses,individuals aged 65 years and older were more susceptible to pollutants such as NO2 and SO2,with most Lag periods(Lag 01 to ag04)showing significantly elevated risks.Conclusion Short-term exposure of gaseous pollutants CO,NO2 and SO2 is significantly related to the number of emergency visits of patients with heart failure,among which males,patients≥65 and patients with recurrent acute heart failure are more susceptible.关键词
急性心力衰竭/空气污染物/一氧化碳/二氧化氮/臭氧/二氧化硫/细颗粒物/可吸入颗粒物Key words
Acute heart failure/Air pollutant/CO/NO2/O3/SO2/PM2.5/PM10引用本文复制引用
郑淑娟,吴昊天,王博,陈隽雯,李欣橦,杨江华,易荣兵,贺晓楠..季风气候地区空气污染物短期暴露与急性心力衰竭患者就诊的相关性分析[J].国际老年医学杂志,2026,47(3):268-278,11.基金项目
国家自然科学基金面上项目(62272327) （62272327）
中华医学会心血管病学分会临床研究专项基金项目(CSCF2024B03) （CSCF2024B03）
北京市医院管理中心临床医学发展专项"杨帆3.0"医工结合培育项目(YGLX202) （YGLX202）
